Title:
NOVEL BUTADIENE DERIVATIVES, PROCESS FOR PREPARATION OF THE SAME AND INTERMEDIATES FOR THE SYNTHESIS THEREOF
Document Type and Number:
WIPO Patent Application WO/2003/004473
Kind Code:
A1
Abstract:
Butadiene derivatives represented by the general formula [I] and having excellent PAI−1 inhibitory activity and so on, or pharmacologically acceptable salts thereof&semi a process for preparing the derivatives or the salts&semi and intermediates for the synthesis of the same: [I] wherein R1 is hydrogen or lower alkyl&semi R2 is lower alkyl&semi R3 is lower alkoxy&semi R4 is hydrogen or lower alkyl&semi and R5 is lower alkyl.
Inventors:
OHTANI AKIO (JP)
OGIKU TSUYOSHI (JP)
YAMADA YASUHIRO (JP)
OGIKU TSUYOSHI (JP)
YAMADA YASUHIRO (JP)
Application Number:
PCT/JP2002/006047
Publication Date:
January 16, 2003
Filing Date:
June 18, 2002
Export Citation:
Assignee:
TANABE SEIYAKU CO (JP)
OHTANI AKIO (JP)
OGIKU TSUYOSHI (JP)
YAMADA YASUHIRO (JP)
OHTANI AKIO (JP)
OGIKU TSUYOSHI (JP)
YAMADA YASUHIRO (JP)
International Classes:
A61P7/02; A61P9/10; A61P29/00; A61P31/04; A61P35/04; A61P37/06; A61P43/00; C07C63/66; C07C69/76; C07C69/94; C07D213/75; (IPC1-7): C07D213/75; A61K31/4409; A61P7/02; A61P9/10; A61P29/00; A61P31/04; A61P35/04; A61P37/06; A61P43/00; C07C69/734; C07C69/76
Domestic Patent References:
| WO1997036864A1 | 1997-10-09 |
Other References:
RAMAIAH DANABOYINA ET AL.: "Phototransformations of epoxyindanone adducts. Steady-state and laser flash photolysis studies", J. ORGANIC CHEMISTRY, vol. 52, no. 6, 1987, pages 1082 - 1089, XP002957171
See also references of EP 1403252A4
See also references of EP 1403252A4
Attorney, Agent or Firm:
Aoyama, Tamotsu (IMP Building 3-7, Shiromi 1-chome, Chuo-k, Osaka-shi Osaka, JP)
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