NOVEL CINNAMIC ACID RELATED COMPOUNDS - SANTEN PHARMACEUTICAL CO LTD

Title:

NOVEL CINNAMIC ACID RELATED COMPOUNDS

Document Type and Number:

WIPO Patent Application WO/2006/011669

Kind Code:

A1

Abstract:

Novel cinnamic acid-related compounds and salts thereof which are useful as drugs, specifically, compounds represented by the general formula [1] and salts thereof: [1] wherein A is a six-membered hydrocarbon ring or a six-membered heterocycle; R^a1 is H, alkyl, or aryl; R^a2 is H, halogeno, OH, or the like; R^a3 is H, halogeno, OH, alkoxy, or the like; R^a4 is carboxy, amino, or the like; X^a is -C(=N-R^a5)-, -CR^a6R^a7-, -NR^a8-, or the like; R^a5 is H, OH, alkoxy, or the like; R^a6 and R^a7 are each H, halogeno, or the like; R^a6 and R^a7 may form a cyclohexane ring; R^a8 is H, OH, alkoxy, or the like; Y^a is alkylene, -O-alkylene, or the like; and the broken line represents a single or double bond.

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Inventors:

TAJIMA HISASHI (JP)
MORI TOSHIYUKI (JP)
MATSUBAYASHI KENICHIRO (JP)
SUHARA HIROSHI (JP)
KIRIHARA TOMOKO (JP)
SHIMAZAKI ATSUSHI (JP)

Application Number:

PCT/JP2005/014262

Publication Date:

February 02, 2006

Filing Date:

July 28, 2005

Export Citation:

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Assignee:

SANTEN PHARMACEUTICAL CO LTD (JP)
TAJIMA HISASHI (JP)
MORI TOSHIYUKI (JP)
MATSUBAYASHI KENICHIRO (JP)
SUHARA HIROSHI (JP)
KIRIHARA TOMOKO (JP)
SHIMAZAKI ATSUSHI (JP)

International Classes:

C07C59/88; A61K31/192; A61K31/216; A61K31/382; A61K31/445; A61K31/495; A61K31/5375; A61P27/06; C07C59/125; C07C59/48; C07C59/64; C07C59/84; C07C69/734; C07C69/738; C07C233/65; C07C251/48; C07C317/44; C07D211/34; C07D213/75; C07D295/10; C07D301/12; C07D303/22; C07D303/32; C07D311/36; C07D335/06

Foreign References:

JPH07258074A	1995-10-09
JP2000256259A	2000-09-19
JPH10509987A	1998-09-29
US3501503A	1970-03-17
US4342782A	1982-08-03
US5506226A	1996-04-09
JP2000063340A	2000-02-29
JPH11514015A	1999-11-30
JP2001139550A	2001-05-22
JP2000336063A	2000-12-05

Attorney, Agent or Firm:

Hibi, Norihiko c/o KISHIMOTO & CO. (3rd Floor Inaba Building, 13-18, Nishishinsaibashi 1-chome, Chuo-k, Osaka-shi Osaka, JP)

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