Title:
NOVEL CINNAMIC ACID RELATED COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2006/011669
Kind Code:
A1
Abstract:
Novel cinnamic acid-related compounds and salts thereof which are useful as drugs, specifically, compounds represented by the general formula [1] and salts thereof: [1] wherein A is a six-membered hydrocarbon ring or a six-membered heterocycle; Ra1 is H, alkyl, or aryl; Ra2 is H, halogeno, OH, or the like; Ra3 is H, halogeno, OH, alkoxy, or the like; Ra4 is carboxy, amino, or the like; Xa is -C(=N-Ra5)-, -CRa6Ra7-, -NRa8-, or the like; Ra5 is H, OH, alkoxy, or the like; Ra6 and Ra7 are each H, halogeno, or the like; Ra6 and Ra7 may form a cyclohexane ring; Ra8 is H, OH, alkoxy, or the like; Ya is alkylene, -O-alkylene, or the like; and the broken line represents a single or double bond.
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Inventors:
TAJIMA HISASHI (JP)
MORI TOSHIYUKI (JP)
MATSUBAYASHI KENICHIRO (JP)
SUHARA HIROSHI (JP)
KIRIHARA TOMOKO (JP)
SHIMAZAKI ATSUSHI (JP)
MORI TOSHIYUKI (JP)
MATSUBAYASHI KENICHIRO (JP)
SUHARA HIROSHI (JP)
KIRIHARA TOMOKO (JP)
SHIMAZAKI ATSUSHI (JP)
Application Number:
PCT/JP2005/014262
Publication Date:
February 02, 2006
Filing Date:
July 28, 2005
Export Citation:
Assignee:
SANTEN PHARMACEUTICAL CO LTD (JP)
TAJIMA HISASHI (JP)
MORI TOSHIYUKI (JP)
MATSUBAYASHI KENICHIRO (JP)
SUHARA HIROSHI (JP)
KIRIHARA TOMOKO (JP)
SHIMAZAKI ATSUSHI (JP)
TAJIMA HISASHI (JP)
MORI TOSHIYUKI (JP)
MATSUBAYASHI KENICHIRO (JP)
SUHARA HIROSHI (JP)
KIRIHARA TOMOKO (JP)
SHIMAZAKI ATSUSHI (JP)
International Classes:
C07C59/88; A61K31/192; A61K31/216; A61K31/382; A61K31/445; A61K31/495; A61K31/5375; A61P27/06; C07C59/125; C07C59/48; C07C59/64; C07C59/84; C07C69/734; C07C69/738; C07C233/65; C07C251/48; C07C317/44; C07D211/34; C07D213/75; C07D295/10; C07D301/12; C07D303/22; C07D303/32; C07D311/36; C07D335/06
Foreign References:
JPH07258074A | 1995-10-09 | |||
JP2000256259A | 2000-09-19 | |||
JPH10509987A | 1998-09-29 | |||
US3501503A | 1970-03-17 | |||
US4342782A | 1982-08-03 | |||
US5506226A | 1996-04-09 | |||
JP2000063340A | 2000-02-29 | |||
JPH11514015A | 1999-11-30 | |||
JP2001139550A | 2001-05-22 | |||
JP2000336063A | 2000-12-05 |
Attorney, Agent or Firm:
Hibi, Norihiko c/o KISHIMOTO & CO. (3rd Floor Inaba Building, 13-18,
Nishishinsaibashi 1-chome, Chuo-k, Osaka-shi Osaka, JP)
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