Title:
NOVEL COMPOSITIONS FOR INHIBITING VIRUS ENTRY AND PROMOTING VIROLYISIS, AND METHODS THEREOF
Document Type and Number:
WIPO Patent Application WO/2012/048033
Kind Code:
A3
Abstract:
The present invention includes a composition comprising a gold nanoparticle compiexed with a cysteine-containing compound. The invention also includes the method of preparing a composition comprising a gold nanoparticle compiexed with a cysteine-containing compound. The invention ftirther includes a method of causing virolysis of a virus using the compositions described therein. The invention ftirther includes a method of inhibiting vims entry using the compositions described therein.
Inventors:
CHAIKEN IRWIN (US)
PAPAZOGLOU ELISABETH (US)
BASTIAN ARANGASSERY ROSEMARY (US)
KANTHARAJU (US)
PAPAZOGLOU ELISABETH (US)
BASTIAN ARANGASSERY ROSEMARY (US)
KANTHARAJU (US)
Application Number:
PCT/US2011/054969
Publication Date:
July 19, 2012
Filing Date:
October 05, 2011
Export Citation:
Assignee:
UNIV DREXEL (US)
PHILADELPHIA HEALTH & EDUCATIO (US)
CHAIKEN IRWIN (US)
PAPAZOGLOU ELISABETH (US)
BASTIAN ARANGASSERY ROSEMARY (US)
KANTHARAJU (US)
PHILADELPHIA HEALTH & EDUCATIO (US)
CHAIKEN IRWIN (US)
PAPAZOGLOU ELISABETH (US)
BASTIAN ARANGASSERY ROSEMARY (US)
KANTHARAJU (US)
International Classes:
A61K38/10; A61K38/00; A61K38/08
Foreign References:
| US20100216721A1 | 2010-08-26 | |||
| US20070054337A1 | 2007-03-08 | |||
| US20060165751A1 | 2006-07-27 |
Other References:
MARTINEZ-AVILA ET AL.: "Gold manno-glyconanoparticles: multivalent systems to block HIV-1 gp120 binding to the lectin DC-SIGN.", CHEM EUR J, vol. 15, 2009, pages 9874 - 9888
Attorney, Agent or Firm:
SYLVA, Domingo J. et al. (LLP300 Four Falls Corporate Center, Suite 710,300 Conshohocken State Roa, West Conshohocken PA, US)
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