Title:
NOVEL COMPOUND, REAGENT COMPRISING THE COMPOUND FOR PEPTIDE OR PROTEIN ANALYSIS, AND METHOD OF ANALYSIS WITH THE ANALYTICAL REAGENT
Document Type and Number:
WIPO Patent Application WO/2006/132030
Kind Code:
A1
Abstract:
A compound represented by the following formula (I), which is useful as a reagent with which the concentrations of a peptide and a protein can be efficiently and easily determined with high sensitivity; and a method of analysis in which a reagent comprising the compound is used. [Chemical formula 1] Formula (I) [In the formula, R1 represents optionally substituted aryl or heteroaryl; R3, R4, R5, and R6 each independently represents a member selected from the group consisting of a bond, hydrogen, C1-10 alkyl, C1-10 alkoxy, phenyl (the phenyl may be substituted by one or more groups selected among amino, halogeno, and nitro), amino, cyano, nitro, carboxy (or a salt, ester, or amide thereof), sulfo (or a salt, ester, or amide thereof), thiol, hydroxy (or a salt thereof), C1-10 acyl, halogeno, and sugar; and n is an integer of 1-5.]
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Inventors:
SUZUKI YOSHIO (JP)
HIRATSUKA ATSUNORI (JP)
YOKOYAMA KENJI (JP)
HIRATSUKA ATSUNORI (JP)
YOKOYAMA KENJI (JP)
Application Number:
PCT/JP2006/307531
Publication Date:
December 14, 2006
Filing Date:
April 10, 2006
Export Citation:
Assignee:
NAT INST OF ADVANCED IND SCIEN (JP)
SUZUKI YOSHIO (JP)
HIRATSUKA ATSUNORI (JP)
YOKOYAMA KENJI (JP)
SUZUKI YOSHIO (JP)
HIRATSUKA ATSUNORI (JP)
YOKOYAMA KENJI (JP)
International Classes:
C07D309/34; G01N21/78; G01N31/22; G01N33/68
Domestic Patent References:
| WO1986006374A1 | 1986-11-06 | |||
| WO2003078542A1 | 2003-09-25 |
Other References:
JUN H. ET AL.: "Fluorescent Hydrophobic Probes Based on Intramolecular Charge Transfer State for Sensitive Protein Detection in Solution", CHEMISTRY LETTERS, vol. 33, no. 6, 2004, pages 690 - 691, XP003001630
WANG B.C. ET AL.: "Theoretical Investigation of Electro-Luminescent Properties in Red Emission DCM, DCJ, RED and DAD Derivatives", THEOCHEM., vol. 716, no. 1-3, 7 March 2005 (2005-03-07), pages 19 - 25, XP004771689
KOPYLOVA T.N. ET AL.: "Limitation of High-Power Radiation by Organic Molecules: I. Substituted Pyranes and Cyanine Dyes", QUANTUM ELECTRONICS, vol. 33, no. 11, 2003, pages 967 - 974, XP003001631
WANG B.C. ET AL.: "Theoretical Investigation of Electro-Luminescent Properties in Red Emission DCM, DCJ, RED and DAD Derivatives", THEOCHEM., vol. 716, no. 1-3, 7 March 2005 (2005-03-07), pages 19 - 25, XP004771689
KOPYLOVA T.N. ET AL.: "Limitation of High-Power Radiation by Organic Molecules: I. Substituted Pyranes and Cyanine Dyes", QUANTUM ELECTRONICS, vol. 33, no. 11, 2003, pages 967 - 974, XP003001631
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