Title:
NOVEL COMPOUNDS THAT INHIBIT FACTOR XA ACTIVITY
Document Type and Number:
WIPO Patent Application WO2003064378
Kind Code:
A3
Abstract:
The invention relates to the compounds of formula (I) or to the pharmaceutically acceptable salts, solvates, hydrates or pharmaceutically acceptable formulations thereof. The inventive compounds can be used to inhibit factor Xa and to prevent and/or treat thrombolytic disorders.
Inventors:
ECKL ROBERT (DE)
SCHABBERT SILKE (DE)
FUCHS THILO (DE)
SCHABBERT SILKE (DE)
FUCHS THILO (DE)
Application Number:
PCT/EP2003/001012
Publication Date:
January 08, 2004
Filing Date:
January 31, 2003
Export Citation:
Assignee:
MORPHOCHEM AG KOMB CHEMIE (DE)
ECKL ROBERT (DE)
SCHABBERT SILKE (DE)
FUCHS THILO (DE)
ECKL ROBERT (DE)
SCHABBERT SILKE (DE)
FUCHS THILO (DE)
International Classes:
C07D295/12; A61K31/167; A61K31/18; A61K31/351; A61K31/495; A61K31/5375; A61K31/7034; A61P7/02; A61P9/10; A61P31/04; A61P35/00; A61P43/00; C07C257/18; C07C311/35; C07C311/37; C07D309/10; C07H15/203; (IPC1-7): C07C257/18; A61K31/165; A61K31/33; C07D295/12
Domestic Patent References:
| WO2002057236A1 | 2002-07-25 | |||
| WO2001070678A2 | 2001-09-27 | |||
| WO2001062717A1 | 2001-08-30 | |||
| WO2000040548A1 | 2000-07-13 | |||
| WO2001014320A1 | 2001-03-01 |
Foreign References:
| EP1078917A1 | 2001-02-28 | |||
| EP0921116A1 | 1999-06-09 |
Other References:
LUTZ WEBER ET AL.: "Optimierung der biologischen Aktivität von kombinatorischen Verbindungsbibliotheken durch einen genetischen Algorithmus", ANGEWANDTE CHEMIE., vol. 107, no. 20, 1995, VCH VERLAGSGESELLSCHAFT, WEINHEIM., DE, pages 2452 - 2454, XP002238358, ISSN: 0044-8249
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