Title:
NOVEL DAHP SYNTHASE VARIANT, AND METHOD FOR PRODUCING L-LYSINE USING SAME
Document Type and Number:
WIPO Patent Application WO/2022/163916
Kind Code:
A1
Abstract:
The present application relates to a 3-deoxy-D-arabinoheptulosonate-7-phosphate (DAHP) synthase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-lysine using the strain.
Inventors:
PARK GOUN (KR)
KIM BYEONG SOO (KR)
LEE HAN HYOUNG (KR)
BAE HYUN WON (KR)
BYUN HYO JEONG (KR)
HUH LAN (KR)
YOO HYERYUN (KR)
KIM BINA (KR)
SON SUNG KWANG (KR)
KIM BYEONG SOO (KR)
LEE HAN HYOUNG (KR)
BAE HYUN WON (KR)
BYUN HYO JEONG (KR)
HUH LAN (KR)
YOO HYERYUN (KR)
KIM BINA (KR)
SON SUNG KWANG (KR)
Application Number:
PCT/KR2021/004164
Publication Date:
August 04, 2022
Filing Date:
April 02, 2021
Export Citation:
Assignee:
CJ CHEILJEDANG CORP (KR)
International Classes:
C12N9/10; C07K14/34; C12N9/02; C12N9/04; C12N9/12; C12N15/77; C12P13/08
Domestic Patent References:
| WO2018226964A2 | 2018-12-13 | |||
| WO2008082181A1 | 2008-07-10 |
Foreign References:
| KR102147776B1 | 2020-08-26 | |||
| KR930013093A | 1993-07-21 | |||
| KR101582008B1 | 2015-12-31 | |||
| US9556463B2 | 2017-01-31 | |||
| US7662943B2 | 2010-02-16 | |||
| US10584338B2 | 2020-03-10 | |||
| US10273491B2 | 2019-04-30 | |||
| KR20200136813A | 2020-12-08 |
Other References:
DATABASE Protein GenPept; 16 December 2020 (2020-12-16), ANONYMOUS : "3-deoxy-7-phosphoheptulonate synthase class II [Corynebacterium glutam]", XP055953530, retrieved from NCBI Database accession no. WP_011014936
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL.: "EMBOSS: The European Molecular Biology Open Software Suite", TRENDS GENET, vol. 16, 2000, pages 276 - 277, XP004200114, DOI: 10.1016/S0168-9525(00)02024-2
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
"Guide to Huge Computers", 1994, ACADEMIC PRESS
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"Atlas Of Protein Sequence And Structure", 1979, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, pages: 353 - 358
"GenBank", Database accession no. WP _011014936.1
J. SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
NAKASHIMA N. ET AL.: "Bacterial cellular engineering by genome editing and gene silencing", INT J MOL SCI, vol. 15, no. 2, 2014, pages 2773 - 51,7-8
SAMBROOK ET AL., MOLECULAR CLONING, 2012
WEINTRAUB, H. ET AL.: "Antisense-RNA as a molecular tool for genetic analysis", REVIEWS-TRENDS IN GENETICS, vol. 1, no. 1, 1986
SITNICKA ET AL., FUNCTIONAL ANALYSIS OF GENES. ADVANCES IN CELL BIOLOGY, vol. 2, 2010, pages 1 - 16
"Manual of Methods for General Bacteriology", 1981, AMERICAN SOCIETY FOR BACTERIOLOGY
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL.: "EMBOSS: The European Molecular Biology Open Software Suite", TRENDS GENET, vol. 16, 2000, pages 276 - 277, XP004200114, DOI: 10.1016/S0168-9525(00)02024-2
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
"Guide to Huge Computers", 1994, ACADEMIC PRESS
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"Atlas Of Protein Sequence And Structure", 1979, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, pages: 353 - 358
"GenBank", Database accession no. WP _011014936.1
J. SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
NAKASHIMA N. ET AL.: "Bacterial cellular engineering by genome editing and gene silencing", INT J MOL SCI, vol. 15, no. 2, 2014, pages 2773 - 51,7-8
SAMBROOK ET AL., MOLECULAR CLONING, 2012
WEINTRAUB, H. ET AL.: "Antisense-RNA as a molecular tool for genetic analysis", REVIEWS-TRENDS IN GENETICS, vol. 1, no. 1, 1986
SITNICKA ET AL., FUNCTIONAL ANALYSIS OF GENES. ADVANCES IN CELL BIOLOGY, vol. 2, 2010, pages 1 - 16
"Manual of Methods for General Bacteriology", 1981, AMERICAN SOCIETY FOR BACTERIOLOGY
Attorney, Agent or Firm:
YOU ME PATENT AND LAW FIRM (KR)
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