NOVEL DECALACTONES FROM ASSOCIATED FUNGI OF MARINE SPONGES AND THEIR SYNTHETIC DERIVATIVES AS MEDICAMENTS

WIPO Patent Application WO2002092589

A3

The invention relates to the isolation, structural determination, synthesis and utilization of decalactones and their derivatives as medicaments. Said novel natural substances were isolated from the culture broth of a fungus, which is present as an associated fungus in a marine sponge. The invention also relates to the synthesis of said natural substances and their derivatives. The disclosed natural substances and synthetic derivatives of said natural substances can be used as active ingredients in medicaments, especially medicaments against cancer diseases and as anti-infectants.

JPH09157168	ANTI-HELICOBACTER PYLORI AGENT AND ITS PRODUCTION
JPH09503757	[Title of the Invention] A novel bishispidine derivative, a method for producing the same, and a pharmaceutical preparation containing the compound thereof.
JP2001527569	INDUSTRIAL APPLICABILITY The pharmaceutical composition containing uscaridine or an analog thereof.

BRINGMANN GERHARD
PROKSCH PETER
HEUBES MARKUS
EDRADA RU ANGELIE
SUDARSONO JALAN KARRTINI
GUENTHER ECKHARD

PCT/EP2002/004676

September 02, 2004

April 27, 2002

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BIOTEC MARIN GMBH (DE)

A61K31/365; A61K36/06; A61P31/04; A61P31/10; A61P33/02; A61P35/00; C07D313/00; C12P17/08; (IPC1-7): C07D313/00; A61K31/365; A61P35/00; C12P17/02

EP0497300A1

1992-08-05

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