Title:
NOVEL DNA POLYMERASE Ⅲ SUBUNITS GAMMA AND TAU VARIANT AND METHOD FOR PRODUCING L-LYSINE USING SAME
Document Type and Number:
WIPO Patent Application WO/2022/154172
Kind Code:
A1
Abstract:
The present application relates to a novel DNA polymerase Ⅲ subunits gamma and tau variant, Corynebacterium stationis strain comprising the variant, and a method for producing L-lysine using the strain.
Inventors:
BAE JEE YEON (KR)
LEE HAN HYOUNG (KR)
BAE HYUN WON (KR)
PARK GOUN (KR)
KIM HYO JIN (KR)
SHIN YONG UK (KR)
LEE HAN HYOUNG (KR)
BAE HYUN WON (KR)
PARK GOUN (KR)
KIM HYO JIN (KR)
SHIN YONG UK (KR)
Application Number:
PCT/KR2021/004018
Publication Date:
July 21, 2022
Filing Date:
March 31, 2021
Export Citation:
Assignee:
CJ CHEILJEDANG CORP (KR)
International Classes:
C12N9/12; C12N15/77; C12P13/08
Domestic Patent References:
| WO2008082181A1 | 2008-07-10 |
Foreign References:
| KR20150000773A | 2015-01-05 | |||
| KR101582008B1 | 2015-12-31 | |||
| KR100838038B1 | 2008-06-12 | |||
| KR940001307A | 1994-01-11 | |||
| US9556463B2 | 2017-01-31 | |||
| US7662943B2 | 2010-02-16 | |||
| US10584338B2 | 2020-03-10 | |||
| US10273491B2 | 2019-04-30 |
Other References:
DATABASE PROTEIN 14 March 2021 (2021-03-14), ANONYMOUS : "DNA polymerase III subunit gamma and tau [Corynebacterium glutamicum] ", XP055951085, retrieved from NCBI Database accession no. WP_011013499
OHNISHI, J. ; KATAHIRA, R. ; MITSUHASHI, S. ; KAKITA, S. ; IKEDA, M.: "A novel gnd mutation leading to increased l-lysine production in Corynebacterium glutamicum", FEMS MICROBIOLOGY LETTERS, NO LONGER PUBLISHED BY ELSEVIER, vol. 242, no. 2, 15 January 2005 (2005-01-15), pages 265 - 274, XP027871638, ISSN: 0378-1097
PEARSON, PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL., TRENDS GENET., vol. 16, 2000, pages 276 - 277
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
GENE, vol. 145, 1994, pages 69 - 73
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"Atlas Of Protein Sequence And Structure", 1979, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, pages: 353 - 358
"GenBank", Database accession no. YP_224542.1
J. SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
NAKASHIMA N.: "Bacterial cellular engineering by genome editing and gene silencing", INT J MOL SCI., vol. 15, no. 2, 2014, pages 2773 - 2793, XP055376889, DOI: 10.3390/ijms15022773
SAMBROOK ET AL.: "Molecular Cloning", 2012
WEINTRAUB, H.: "Antisense-RNA as a molecular tool for genetic analysis", REVIEWS-TRENDS IN GENETICS, vol. 1, no. 1, 1986
SITNICKA ET AL.: "Functional Analysis of Genes", ADVANCES IN CELL BIOLOGY, vol. 2, 2010, pages 1 - 16
"Manual of Methods for General Bacteriology", 1981, AMERICAN SOCIETY FOR BACTERIOLOGY
See also references of EP 4050104A4
OHNISHI, J. ; KATAHIRA, R. ; MITSUHASHI, S. ; KAKITA, S. ; IKEDA, M.: "A novel gnd mutation leading to increased l-lysine production in Corynebacterium glutamicum", FEMS MICROBIOLOGY LETTERS, NO LONGER PUBLISHED BY ELSEVIER, vol. 242, no. 2, 15 January 2005 (2005-01-15), pages 265 - 274, XP027871638, ISSN: 0378-1097
PEARSON, PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL., TRENDS GENET., vol. 16, 2000, pages 276 - 277
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
GENE, vol. 145, 1994, pages 69 - 73
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"Atlas Of Protein Sequence And Structure", 1979, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, pages: 353 - 358
"GenBank", Database accession no. YP_224542.1
J. SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
NAKASHIMA N.: "Bacterial cellular engineering by genome editing and gene silencing", INT J MOL SCI., vol. 15, no. 2, 2014, pages 2773 - 2793, XP055376889, DOI: 10.3390/ijms15022773
SAMBROOK ET AL.: "Molecular Cloning", 2012
WEINTRAUB, H.: "Antisense-RNA as a molecular tool for genetic analysis", REVIEWS-TRENDS IN GENETICS, vol. 1, no. 1, 1986
SITNICKA ET AL.: "Functional Analysis of Genes", ADVANCES IN CELL BIOLOGY, vol. 2, 2010, pages 1 - 16
"Manual of Methods for General Bacteriology", 1981, AMERICAN SOCIETY FOR BACTERIOLOGY
See also references of EP 4050104A4
Attorney, Agent or Firm:
YOU ME PATENT AND LAW FIRM (KR)
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