NOVEL ESTRADIOL DERIVATIVES - NIPPON ORGANON K K

Title:

NOVEL ESTRADIOL DERIVATIVES

Document Type and Number:

WIPO Patent Application WO/2000/053620

Kind Code:

A1

Abstract:

Estradiol derivatives represented by general formula (I) (wherein R is optionally substituted phenyl). These derivatives (I) act as steroid sulfatase inhibitors and thus are efficacious against estrone-dependent diseases such as mammary cancer, endometrial cancer, endometriosis, uterus myoma and so on.

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Inventors:

JINBO YOSHIKAZU (JP)
INOUE YOSHIMASA (JP)

Application Number:

PCT/JP2000/001410

Publication Date:

September 14, 2000

Filing Date:

March 08, 2000

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Assignee:

NIPPON ORGANON K K (JP)
JINBO YOSHIKAZU (JP)
INOUE YOSHIMASA (JP)

International Classes:

C07J31/00; (IPC1-7): C07J31/00

Domestic Patent References:

WO1998011124A1

1998-03-19

Foreign References:

US5616574A

1997-04-01

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