Title:
NOVEL FORMULATIONS OF EPINEPHRINE AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/082281
Kind Code:
A1
Abstract:
Provided herein are novel formulations of epinephrine that comprise polyoxymethylene alkyl ethers as a permeation enhancer, methods of administering the formulation, and uses thereof.
Inventors:
WANG LIKUN (CN)
SHI HAORU (CN)
SHI HAORU (CN)
Application Number:
PCT/CN2022/126776
Publication Date:
April 25, 2024
Filing Date:
October 21, 2022
Export Citation:
Assignee:
NANJING HAIWEI PHARMACEUTICAL TECH CO LTD (CN)
International Classes:
A61K31/137; A61K47/02; A61K47/10; A61P37/00; A61P37/08
Domestic Patent References:
| WO2019157099A1 | 2019-08-15 | |||
| WO2001021152A1 | 2001-03-29 |
Foreign References:
| US20180169247A1 | 2018-06-21 | |||
| US20100215730A1 | 2010-08-26 |
Other References:
BARRY E. BLESKE: "Effect of Vehicle on the Nasal Absorption of Epinephrine During Cardiopulmonary Resuscitation", PHARMACOTHERAPY, WILEY-BLACKWELL, US, vol. 16, no. 6, 12 November 1996 (1996-11-12), US , pages 1039 - 1045, XP093161176, ISSN: 0277-0008, DOI: 10.1002/j.1875-9114.1996.tb03030.x
RICHARD D. ENNIS: "The effects of permeation enhancers on the surface morphology of the rat nasal mucosa: A scanning electron microscopy study", PHARMACEUTICAL RESEARCH, vol. 7, no. 5, 1 January 1990 (1990-01-01), pages 468 - 475, XP093161178
RICHARD D. ENNIS: "The effects of permeation enhancers on the surface morphology of the rat nasal mucosa: A scanning electron microscopy study", PHARMACEUTICAL RESEARCH, vol. 7, no. 5, 1 January 1990 (1990-01-01), pages 468 - 475, XP093161178
Attorney, Agent or Firm:
WU, FENG & ZHANG (CN)
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