Title:
NOVEL GPCR-LIKE PROTEINS AND NUCLEIC ACIDS ENCODING SAME
Document Type and Number:
WIPO Patent Application WO2002070707
Kind Code:
A3
Abstract:
Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
Inventors:
PADIGARU MURALIDHARA (US)
GERLACH VALERIE L (US)
SMITHSON GLENNDA (US)
STONE DAVID (US)
BIN-YANG RUEY (US)
CONLEY PAMELA (US)
HART MATTHEW (US)
TOMLINSON JAMES E (US)
TOPPER JAMES N (US)
KEKUDA RAMESH (US)
CASMAN STACIE J (US)
EDINGER SCHLOMIT (US)
MACDOUGALL JOHN R (US)
GERLACH VALERIE L (US)
SMITHSON GLENNDA (US)
STONE DAVID (US)
BIN-YANG RUEY (US)
CONLEY PAMELA (US)
HART MATTHEW (US)
TOMLINSON JAMES E (US)
TOPPER JAMES N (US)
KEKUDA RAMESH (US)
CASMAN STACIE J (US)
EDINGER SCHLOMIT (US)
MACDOUGALL JOHN R (US)
Application Number:
PCT/US2001/049168
Publication Date:
July 31, 2003
Filing Date:
December 18, 2001
Export Citation:
Assignee:
CURAGEN CORP (US)
COR THERAPEUTICS INC (US)
PADIGARU MURALIDHARA (US)
GERLACH VALERIE L (US)
SMITHSON GLENNDA (US)
STONE DAVID (US)
BIN-YANG RUEY (US)
CONLEY PAMELA (US)
HART MATTHEW (US)
TOMLINSON JAMES E (US)
TOPPER JAMES N (US)
KEKUDA RAMESH (US)
CASMAN STACIE J (US)
EDINGER SCHLOMIT (US)
MACDOUGALL JOHN R (US)
COR THERAPEUTICS INC (US)
PADIGARU MURALIDHARA (US)
GERLACH VALERIE L (US)
SMITHSON GLENNDA (US)
STONE DAVID (US)
BIN-YANG RUEY (US)
CONLEY PAMELA (US)
HART MATTHEW (US)
TOMLINSON JAMES E (US)
TOPPER JAMES N (US)
KEKUDA RAMESH (US)
CASMAN STACIE J (US)
EDINGER SCHLOMIT (US)
MACDOUGALL JOHN R (US)
International Classes:
C07K14/705; C12N15/12; A61K38/00; (IPC1-7): C12N15/12; C07K14/705; C12N15/63; C07K16/28; G01N33/53; C12Q1/68; G01N33/50; A61K38/17; A61K39/395; A61K31/7088
Domestic Patent References:
| WO2001027158A2 | 2001-04-19 |
Foreign References:
| EP0867508A2 | 1998-09-30 |
Other References:
MOMBAERTS P: "MOLECULAR BIOLOGY OF ODORANT RECEPTORS IN VERTEBRATES", ANNUAL REVIEW OF NEUROSCIENCE, ANNUAL REVIEWS INC., PALO ALTO, CA, US, vol. 22, 1999, pages 487 - 509, XP000891908, ISSN: 0147-006X
HERZ J M ET AL: "MOLECULAR APPROACHES TO RECEPTORS AS TARGETS FOR DRUG DISCOVERY", JOURNAL OF RECEPTOR AND SIGNAL TRANSDUCTION RESEARCH, MARCEL DEKKER, NEW YORK, NY, US, vol. 17, no. 5, 1997, pages 671 - 676, XP001027053, ISSN: 1079-9893
HATT H ET AL: "CLONING, FUNCTIONAL EXPRESSION AND CHARACTERIZATION OF A HUMAN OLFACTORY RECEPTOR", CELLULAR AND MOLECULAR BIOLOGY, CMB ASSOCIATIONS, NOISY-LE-GRAND, FR, vol. 45, no. 3, 1999, pages 285 - 291, XP000891909, ISSN: 0145-5680
HERZ J M ET AL: "MOLECULAR APPROACHES TO RECEPTORS AS TARGETS FOR DRUG DISCOVERY", JOURNAL OF RECEPTOR AND SIGNAL TRANSDUCTION RESEARCH, MARCEL DEKKER, NEW YORK, NY, US, vol. 17, no. 5, 1997, pages 671 - 676, XP001027053, ISSN: 1079-9893
HATT H ET AL: "CLONING, FUNCTIONAL EXPRESSION AND CHARACTERIZATION OF A HUMAN OLFACTORY RECEPTOR", CELLULAR AND MOLECULAR BIOLOGY, CMB ASSOCIATIONS, NOISY-LE-GRAND, FR, vol. 45, no. 3, 1999, pages 285 - 291, XP000891909, ISSN: 0145-5680
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