NOVEL HIGH-EFFICIENCY ANTIMALARIAL DRUG, QUISINOSTAT

WIPO Patent Application WO/2017/143964

A1

The present invention provides a novel high-efficiency antimalarial drug, and specifically, the present invention provides applications of Quisinostat, analogs thereof, or pharmaceutically acceptable salts thereof in treating malaria. The present invention also provides a pharmaceutical composition containing Quisinostat. By means of in-depth researches, it is found that Quisinostat has significant inhibitory effects on plasmodia, and even shows better plasmodium killing effects than artemisinin in mice.

WO/2004/092147	M-STAGE KINESIN INHIBITOR
WO/2005/111016	PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH
WO/2021/225798	SUBSTITUTED {5-METHOXY-6-[(5-METHOXYPYRIDIN-2-YL)METHOXY]PYRIDIN-3-YL}METHYL COMPOUNDS AS CSF-1R INHIBITORS

JIANG LUBIN (CN)
HAUNG ZHENGHUI (CN)

PCT/CN2017/074255

August 31, 2017

February 21, 2017

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INST PASTEUR OF SHANGHAI CHINESE ACAD OF SCIENCES (CN)

A61K31/506; A61K31/137; A61K31/496; A61P33/06

CN1993353A	2007-07-04
CN101516374A	2009-08-26

GU, HUAWEI ET AL.: "Research progress of histone deacetylase inhibitors", CHINA MODERN MEDICINE, vol. 22, no. 16, 30 June 2015 (2015-06-30), pages 15 - 21
GIANNINI, GIUSEPPE ET AL.: "Hydroxamic acid based histone deacetylase inhibitors with confirmed activity against the malaria parasite", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 25, no. 3, 19 December 2014 (2014-12-19), pages 459 - 461, XP029131262
HAN, TAO ET AL.: "jian3shu4shi3yong4qing1hao1su41ian2he2xi1yao4zhi41iao2nve4ji2de1yan2jiu1jin4zhan3", CONTEMPORARY MEDICINE FORUM, vol. 13, no. 6, 31 December 2015 (2015-12-31), pages 10 - 11

XU & PARTNERS,LLC. (CN)

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