Title:
A NOVEL HUMAN PURINERGIC P2U RECEPTOR
Document Type and Number:
WIPO Patent Application WO1996038558
Kind Code:
A3
Abstract:
The present invention provides nucleotide and amino acid sequences that identify and encode a novel purinergic PU2 receptor (PNR) expressed in human placenta. The present invention also provides for antisense molecules to the nucleotide sequences which encode PNR, expression vectors for the production of purified PNR, antibodies capable of binding specifically to PNR, hybridization probes or oligonucleotides for the detection of PNR-encoding nucleotide sequences, genetically engineered host cells for the expression of PNR, and diagnostic tests based on PNR-encoding nucleic acid molecules or antibodies produced against the polypeptide PNR.
Inventors:
COLEMAN ROGER
AU-YOUNG JANICE
STUART SUSAN G
AU-YOUNG JANICE
STUART SUSAN G
Application Number:
PCT/US1996/008481
Publication Date:
January 23, 1997
Filing Date:
June 03, 1996
Export Citation:
Assignee:
INCYTE PHARMA INC (US)
International Classes:
G01N33/50; A61K38/00; A61K45/00; A61K48/00; A61P9/12; A61P35/00; A61P43/00; C07K14/47; C07K14/705; C07K16/28; C12N1/21; C12N5/10; C12N9/64; C12N15/00; C12N15/09; C12N15/10; C12N15/12; C12P21/02; C12Q1/68; G01N33/53; G01N33/566; C12R1/92; (IPC1-7): C12N15/12; C12N15/11; C07K14/705; G01N33/68; A61K38/17; C07K16/28
Domestic Patent References:
| WO1996005302A1 | 1996-02-22 |
Other References:
CHANG,K. ET AL.: "Molecular cloning and functional analysis of a novel P2 nucleotide receptor", JOURNAL OF BIOLOGICAL CHEMISTRY (MICROFILMS), vol. 270, 1994, MD US, pages 25152 - 25158, XP000611453
EMBL EST, Accession no X97058, sequence reference g1296659, 03-MAY-96, Homo sapiens mRNA for P2Y6 gene
EMBL EST, Accession no X97058, sequence reference g1296659, 03-MAY-96, Homo sapiens mRNA for P2Y6 gene
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