NOVEL ION STORAGE SYSTEM AND METHOD BASED ON QUADRUPOLE-ION TRAP TANDEM MASS SPECTROMETRY

Title:

NOVEL ION STORAGE SYSTEM AND METHOD BASED ON QUADRUPOLE-ION TRAP TANDEM MASS SPECTROMETRY

Document Type and Number:

WIPO Patent Application WO/2022/007424

Kind Code:

A1

Abstract:

The present invention relates to the technical field of mass spectra. Disclosed are a novel ion storage system and method based on a quadrupole-ion trap tandem mass spectrometry. The system sequentially comprises a heating capillary, a tube lens, a skimmer, a first ion guide, a second ion guide, a quadrupole mass analyzer, an ion trap mass analyzer, and a detector; a first lens is provided between the first ion guide and the second ion guide; a second lens and a third lens are provided between the second ion guide and the quadrupole mass analyzer, wherein operation modes of the first ion guide and the second ion guide comprise an ion transmission mode and an ion storage mode. Compared with conventional time sequence control methods, more ions are stored during the same time according to the present invention, thereby improving the sensitivity of the instrument.

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Inventors:

CHU SHIYING (CN)
JIANG YOU (CN)
FANG XIANG (CN)
HUANG ZEJIAN (CN)
DAI XINHUA (CN)
AN YUTING (CN)
ZHANG DI (CN)

Application Number:

PCT/CN2021/080045

Publication Date:

January 13, 2022

Filing Date:

March 10, 2021

Export Citation:

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Assignee:

NAT INST METROLOGY CHINA (CN)

International Classes:

H01J49/42

Foreign References:

CN111933512A	2020-11-13
CN110610847A	2019-12-24
US5179278A	1993-01-12
CN105655224A	2016-06-08
US5811800A	1998-09-22

Other References:

CHU SHIYING: "Research on Collision-induced Dissociation Technology within Quadrupole-Linear Ion Trap Mass Spectrometry", SCIENCE-ENGINEERING (A), CHINA MASTER’S THESES FULL-TEXT DATABASE, 15 November 2019 (2019-11-15), XP055886015

Attorney, Agent or Firm:

BEIJING JINZHIPUHUA INTELLECTUAL PROPERTY AGENCY CO. LTD et al. (CN)

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