Title:
NOVEL KETO-OXADIAZOLE DERIVATIVES AS CATHEPSIN INHIBITORS
Document Type and Number:
WIPO Patent Application WO2005040142
Kind Code:
B1
Abstract:
Novel difluorinated amide derivatives of Formula (II) as inhibitors of cathepsin S, K, B, and L, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.
Inventors:
THURAIRATNAM SUKANTHINI (US)
ALDOUS DAVID JOHN (US)
LEROY VINCENT (US)
TIMM ANDREAS PAUL (US)
ALDOUS DAVID JOHN (US)
LEROY VINCENT (US)
TIMM ANDREAS PAUL (US)
Application Number:
PCT/US2004/035282
Publication Date:
July 14, 2005
Filing Date:
October 22, 2004
Export Citation:
Assignee:
AVENTIS PHARMA INC (US)
THURAIRATNAM SUKANTHINI (US)
ALDOUS DAVID JOHN (US)
LEROY VINCENT (US)
TIMM ANDREAS PAUL (US)
THURAIRATNAM SUKANTHINI (US)
ALDOUS DAVID JOHN (US)
LEROY VINCENT (US)
TIMM ANDREAS PAUL (US)
International Classes:
A61K31/5377; C07D261/08; C07D263/32; C07D263/56; C07D267/10; C07D271/06; C07D271/10; C07D271/107; C07D295/195; C07D295/215; C07D413/04; C07D413/12; C07K5/06; A61K38/00; (IPC1-7): C07D271/06; A61K31/5377; A61P35/00; C07D271/10; C07D261/08; C07D413/04; C07D263/32; C07D263/56; C07D295/18; A61P29/00; A61P37/00
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