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Title:
NOVEL LACTIC ACID BACTERIA, AND COMPOSITION, FOOD/DRINK ITEM, AND PHARMACEUTICAL ITEM CONTAINING LACTIC ACID BACTERIA
Document Type and Number:
WIPO Patent Application WO/2023/218898
Kind Code:
A1
Abstract:
The present invention provides: lactic acid bacteria that enhance IL-12p70 and IFN-λ production, thereby making it possible to increases resistance against infection by infectious microorganisms and viruses, relieve stress, and suppress excessive inflammatory response that causes symptoms to worsen; compositions such as a immunostimulation composition, a stress relief composition, and an inflammation suppression composition, containing said lactic acid bacteria; and food/drink and pharmaceutical items containing the compositions. Lactobacillus sakei strain MG-LAB279 (accession number: NITE BP-03645); compositions such as an immunostimulation composition, a stress relief composition, and an inflammation suppression composition containing, as an active ingredient, said strain or a bacterial cell component thereof; and food/drink and pharmaceutical items containing the compositions.

Inventors:
SUGIMOTO ATSUSHI (JP)
NAKAMURA TOMOE (JP)
CHIHAMA RYOTA (JP)
TAKENAKA YUTO (JP)
SATO YUUKI (JP)
Application Number:
PCT/JP2023/015823
Publication Date:
November 16, 2023
Filing Date:
April 20, 2023
Export Citation:
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Assignee:
MITSUBISHI GAS CHEMICAL CO (JP)
International Classes:
A61P3/02; A23L33/135; A61K35/747; A61P31/12; A61P37/04; A61P43/00; C12N1/20; C12R1/225
Foreign References:
JP2009254236A2009-11-05
Other References:
KIM SEO-YEON, SHIN JI-SUN, CHUNG KYUNG-SOOK, HAN HEE-SOO, LEE HWI-HO, LEE JEONG-HUN, KIM SU-YEON, JI YONG WOO, HA YEJIN, KANG JOOY: "Immunostimulatory Effects of Live Lactobacillus sakei K040706 on the CYP-Induced Immunosuppression Mouse Model", NUTRIENTS, M D P I AG, CH, vol. 12, no. 11, 22 November 2020 (2020-11-22), CH , pages 3573, XP093108333, ISSN: 2072-6643, DOI: 10.3390/nu12113573
YOON-DOO LEE, YI-FAN HONG, BORAM JEON, BONG JUN JUNG, DAE KYUN CHUNG, HANGEUN KIM: "Differential Cytokine Regulatory Effect of Three Lactobacillus Strains Isolated from Fermented Foods", JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, HAN'GUG MI'SAENGMUL SAENGMYEONG GONG HAGHOE,KOREAN SOCIETY FOR MICROBIOLOGY AND BIOTECHNOLOGY, KOREA, vol. 26, no. 9, 28 September 2016 (2016-09-28), Korea, pages 1517 - 1526, XP055670405, ISSN: 1017-7825, DOI: 10.4014/jmb.1601.01044
HONG YI-FAN, KIM HANGEUN, KIM HYE RIM, GIM MIN GEUN, CHUNG DAE KYUN: "Different Immune Regulatory Potential of Lactobacillus plantarum and Lactobacillus sakei Isolated from Kimchi", JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, HAN'GUG MI'SAENGMUL SAENGMYEONG GONG HAGHOE,KOREAN SOCIETY FOR MICROBIOLOGY AND BIOTECHNOLOGY, KOREA, vol. 24, no. 12, 28 December 2014 (2014-12-28), Korea, pages 1629 - 1635, XP093108342, ISSN: 1017-7825, DOI: 10.4014/jmb.1406.06062
HALLER D., BLUM S., BODE C., HAMMES W. P., SCHIFFRIN E. J.: "Activation of Human Peripheral Blood Mononuclear Cells by Nonpathogenic Bacteria In Vitro: Evidence of NK Cells as Primary Targets", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 68, no. 2, 1 February 2000 (2000-02-01), US , pages 752 - 759, XP093108829, ISSN: 0019-9567, DOI: 10.1128/IAI.68.2.752-759.2000
Attorney, Agent or Firm:
INABA, Yoshiyuki et al. (JP)
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