Title:
NOVEL LINKER FOR ANTIGEN DETECTION AND ANTIGEN DETECTION METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2022/102791
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide an antigen measurement system capable of rapid, high-sensitivity detection. Specifically, the present invention provides a novel linker for antigen detection, the linker having a main chain and a side chain, wherein: (1) the main chain is provided with a side-chain binding site, an mRNA binding region containing a first crosslinking compound, a DNA binding region for fluorescence detection containing a second crosslinking compound, a solid-phase cleavage site located on the 5' side of the DNA binding region for fluorescence detection, and a solid-phase binding site located at the 5' end of the main chain; and (2) the side chain is provided with a main-chain binding site and a peptide presentation site. The present invention also provides an antigen detection method using the linker.
Inventors:
NEMOTO NAOTO (JP)
HIGASHIDE SO (JP)
HIGASHIDE SO (JP)
Application Number:
PCT/JP2021/042138
Publication Date:
May 19, 2022
Filing Date:
November 16, 2021
Export Citation:
Assignee:
NATIONAL UNIV CORPORATION SAITAMA UNIV (JP)
EPSILON MOLECULAR ENG INC (JP)
EPSILON MOLECULAR ENG INC (JP)
International Classes:
C12N15/11; C12N15/115; C12Q1/6804
Domestic Patent References:
| WO2017170776A1 | 2017-10-05 | |||
| WO2016159211A1 | 2016-10-06 |
Foreign References:
| JP2017035063A | 2017-02-16 |
Attorney, Agent or Firm:
KAWAGUTI & PARTNERS (JP)
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