Title:
NOVEL MICROORGANISM AND METHOD FOR PRODUCING DODECAHYDRO-3A,6,6,9A-TETRAMETHYLNAPHTHO[2,1-B]-FURAN INTERMEDIATE USING THE SAME
Document Type and Number:
WIPO Patent Application WO/2007/097106
Kind Code:
A1
Abstract:
By using sclareol as a substrate, a dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]-furan intermediate is efficiently produced. As a result of intensive studies with the aim of isolating and identifying a microorganism having a characteristic of interest, a plurality of novel microorganisms having the characteristic of interest which are not categorized into conventionally known microorganisms were isolated and identified. The novel microorganism according to the invention belongs to the Ascomycetes and has an ability to produce a dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1,b]-furan intermediate using sclareol as a substrate. The microorganism belonging to the Ascomycetes with such an ability is a new finding and can be a useful microorganism for the production of dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1,b]-furan or an intermediate thereof.
Inventors:
IGARASHI KAZUAKI (JP)
TAKIZAWA SHUICHI (JP)
HIGAKI NORIHIKO (JP)
HAGIHARA HIROSHI (JP)
TAKIZAWA SHUICHI (JP)
HIGAKI NORIHIKO (JP)
HAGIHARA HIROSHI (JP)
Application Number:
PCT/JP2006/325516
Publication Date:
August 30, 2007
Filing Date:
December 21, 2006
Export Citation:
Assignee:
KAO CORP (JP)
IGARASHI KAZUAKI (JP)
TAKIZAWA SHUICHI (JP)
HIGAKI NORIHIKO (JP)
HAGIHARA HIROSHI (JP)
IGARASHI KAZUAKI (JP)
TAKIZAWA SHUICHI (JP)
HIGAKI NORIHIKO (JP)
HAGIHARA HIROSHI (JP)
International Classes:
C12P7/02; C12N1/16; C12P17/04
Foreign References:
| JPS6274281A | 1987-04-06 | |||
| JPH03224478A | 1991-10-03 | |||
| JPH04126023A | 1992-04-27 | |||
| JP2547713B2 | 1996-10-23 | |||
| JP2802588B2 | 1998-09-24 | |||
| JPH032654B2 | 1991-01-16 | |||
| JPH0263550A | 1990-03-02 | |||
| JP2006048550A | 2006-02-16 |
Other References:
ARANDA G. ET AL.: "Microbial transformation of diterpenes: Hydroxylation of sclareol, manool and derivatives by Mucor plumbeus", TETRAHEDRON, vol. 47, no. 39, 1991, pages 8339 - 8350, XP003017242
ARANDA G. ET AL.: "Microbial hydroxylation of sclareol by mucor plumbeus", TETRAHEDRON LETTERS, vol. 32, no. 15, 1991, pages 1783 - 1786, XP003017243
See also references of EP 1997879A4
ARANDA G. ET AL.: "Microbial hydroxylation of sclareol by mucor plumbeus", TETRAHEDRON LETTERS, vol. 32, no. 15, 1991, pages 1783 - 1786, XP003017243
See also references of EP 1997879A4
Attorney, Agent or Firm:
HIRAKI, Yusuke et al. (3-20 Toranomon 4-chom, Minato-ku Tokyo 01, JP)
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