Title:
NOVEL OMEGA-3 AND OMEGA-6 FATTY ACID COMPOSITIONS AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2012/049222
Kind Code:
A3
Abstract:
A composition for use in preventing and/or treating and/or reducing organic, including symptomatic, mental disorders, comprising: a) Docosahexaenoic acid (DHA) and/or the pharmaceutically acceptable derivatives and/or precursors thereof; b) Eicosapentaenoic acid (EPA) and/or the pharmaceutically acceptable derivatives and/or precursors thereof; c) γ-linolenic acid (GLA) and/or the pharmaceutically acceptable derivatives and/or precursors thereof; and at least one vitamin selected from vitamin B6, folic acid, vitamin B12, vitamin E, and/or vitamin D, at least one mineral which is selenium and/or zinc, optionally other vitamins, and optionally a polyphenolic plant extract with antioxidant properties.
Inventors:
TERREAUX CHRISTIAN (CH)
HOMBERGER ELEONORA (CH)
KRIWET BURKHARD (DE)
ECKERT ANNE (CH)
HOMBERGER ELEONORA (CH)
KRIWET BURKHARD (DE)
ECKERT ANNE (CH)
Application Number:
PCT/EP2011/067838
Publication Date:
June 28, 2012
Filing Date:
October 12, 2011
Export Citation:
Assignee:
VIFOR SA (CH)
TERREAUX CHRISTIAN (CH)
HOMBERGER ELEONORA (CH)
KRIWET BURKHARD (DE)
ECKERT ANNE (CH)
TERREAUX CHRISTIAN (CH)
HOMBERGER ELEONORA (CH)
KRIWET BURKHARD (DE)
ECKERT ANNE (CH)
International Classes:
A61K31/4415; A23L1/30; A61K31/202; A61K31/355; A61K33/04; A61K33/30; A61K36/82; A61P25/28
Domestic Patent References:
| WO2001084961A2 | 2001-11-15 | |||
| WO2002052955A1 | 2002-07-11 |
Foreign References:
| EP1800675A1 | 2007-06-27 | |||
| DE202007013532U1 | 2007-12-13 | |||
| EP0440341A1 | 1991-08-07 |
Other References:
CHIU C C ET AL: "The effects of omega-3 fatty acids monotherapy in Alzheimer's disease and mild cognitive impairment: A preliminary randomized double-blind placebo-controlled study", PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, OXFORD, GB, vol. 32, no. 6, 1 August 2008 (2008-08-01), pages 1538 - 1544, XP023181335, ISSN: 0278-5846, [retrieved on 20080525], DOI: 10.1016/J.PNPBP.2008.05.015
FREUND-LEVI YVONNE ET AL: "omega-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease: OmegAD study - A randomized double-blind trial", ARCHIVES OF NEUROLOGY, vol. 63, no. 10, October 2006 (2006-10-01), pages 1402 - 1408,E1, XP002675303, ISSN: 0003-9942
HASHIMOTO M ET AL: "Effects of administration of fish sausage enriched with docosahexaenoic acid on cognitive function in elderly people with very mild dementia", ALZHEIMER'S & DEMENTIA: THE JOURNAL OF THE ALZHEIMER'SASSOCIATION, ELSEVIER, NEW YORK, NY, US, vol. 6, no. 4, 1 July 2010 (2010-07-01), pages S174, XP027439073, ISSN: 1552-5260, [retrieved on 20100701], DOI: 10.1016/J.JALZ.2010.05.549
KIDD P M: "Alzheimer's disease, amnestic mild cognitive impairment, and age-associated memory impairment: Current understanding and progress toward integrative prevention", ALTERNATIVE MEDICINE REVIEW, THORNE RESEARCH INC., SANDPOINT, US, vol. 13, no. 2, 1 June 2008 (2008-06-01), pages 85 - 115, XP009158591, ISSN: 1089-5159
DARVESH A S ET AL: "Oxidative stress and Alzheimer's disease: Dietary polyphenols as potential therapeutic agents", EXPERT REVIEW OF NEUROTHERAPEUTICS, FUTURE DRUGS, LONDON, GB, vol. 10, no. 5, 1 January 2010 (2010-01-01), pages 729 - 745, XP009135022, ISSN: 1473-7175
K. REZAI-ZADEH: "Green Tea Epigallocatechin-3-Gallate (EGCG) Modulates Amyloid Precursor Protein Cleavage and Reduces Cerebral Amyloidosis in Alzheimer Transgenic Mice", JOURNAL OF NEUROSCIENCE, vol. 25, no. 38, 21 September 2005 (2005-09-21), pages 8807 - 8814, XP055001561, ISSN: 0270-6474, DOI: 10.1523/JNEUROSCI.1521-05.2005
FREUND-LEVI YVONNE ET AL: "omega-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease: OmegAD study - A randomized double-blind trial", ARCHIVES OF NEUROLOGY, vol. 63, no. 10, October 2006 (2006-10-01), pages 1402 - 1408,E1, XP002675303, ISSN: 0003-9942
HASHIMOTO M ET AL: "Effects of administration of fish sausage enriched with docosahexaenoic acid on cognitive function in elderly people with very mild dementia", ALZHEIMER'S & DEMENTIA: THE JOURNAL OF THE ALZHEIMER'SASSOCIATION, ELSEVIER, NEW YORK, NY, US, vol. 6, no. 4, 1 July 2010 (2010-07-01), pages S174, XP027439073, ISSN: 1552-5260, [retrieved on 20100701], DOI: 10.1016/J.JALZ.2010.05.549
KIDD P M: "Alzheimer's disease, amnestic mild cognitive impairment, and age-associated memory impairment: Current understanding and progress toward integrative prevention", ALTERNATIVE MEDICINE REVIEW, THORNE RESEARCH INC., SANDPOINT, US, vol. 13, no. 2, 1 June 2008 (2008-06-01), pages 85 - 115, XP009158591, ISSN: 1089-5159
DARVESH A S ET AL: "Oxidative stress and Alzheimer's disease: Dietary polyphenols as potential therapeutic agents", EXPERT REVIEW OF NEUROTHERAPEUTICS, FUTURE DRUGS, LONDON, GB, vol. 10, no. 5, 1 January 2010 (2010-01-01), pages 729 - 745, XP009135022, ISSN: 1473-7175
K. REZAI-ZADEH: "Green Tea Epigallocatechin-3-Gallate (EGCG) Modulates Amyloid Precursor Protein Cleavage and Reduces Cerebral Amyloidosis in Alzheimer Transgenic Mice", JOURNAL OF NEUROSCIENCE, vol. 25, no. 38, 21 September 2005 (2005-09-21), pages 8807 - 8814, XP055001561, ISSN: 0270-6474, DOI: 10.1523/JNEUROSCI.1521-05.2005
Attorney, Agent or Firm:
LECCA, Patricia (21 rue de Fecamp, Paris, FR)
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