Title:
NOVEL PHARMACEUTICAL COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2020/222302
Kind Code:
A1
Abstract:
The present invention relates to a pharmaceutical composition that is used for treating or preventing acidosis of chronic kidney disease with anemia and contains citric acid, a pharmaceutically acceptable salt of citric acid, a hydrate thereof, or a mixture thereof, wherein the pharmaceutical composition is in the form of a tablet.
Inventors:
ABE MICHIAKI (JP)
KOSHIBA SEIZO (JP)
NISHIOKA KOICHIRO (JP)
KAWAGUCHI KAZUHIKO (JP)
YAMASAKI SATOMI (JP)
TERANAKA YASUYUKI (JP)
KOSHIBA SEIZO (JP)
NISHIOKA KOICHIRO (JP)
KAWAGUCHI KAZUHIKO (JP)
YAMASAKI SATOMI (JP)
TERANAKA YASUYUKI (JP)
Application Number:
PCT/JP2020/017690
Publication Date:
November 05, 2020
Filing Date:
April 24, 2020
Export Citation:
Assignee:
UNIV TOHOKU (JP)
NIPPON CHEMIPHAR CO (JP)
NIPPON CHEMIPHAR CO (JP)
International Classes:
A61P7/06; A61K31/194; A61P13/12
Domestic Patent References:
| WO2018193648A1 | 2018-10-25 | |||
| WO2018193752A1 | 2018-10-25 |
Foreign References:
| JP2018177752A | 2018-11-15 | |||
| JP2009525276A | 2009-07-09 | |||
| JP2019086945A | 2019-06-06 | |||
| JP2019119297A | 2019-07-22 |
Other References:
GADOLA, LILIANA ET AL.: "Calcium citrate ameliorates the progression of chronic renal injury", KIDNEY INTERNATIONAL, vol. 65, no. Issue 4, April 2004 (2004-04-01), pages 1224 - 1230, XP009108222, DOI: 10.1111/j.1523-1755.2004.00496.x
TOMOAKI ABE, DAISUKE SAEGUSA, SEIZO KOSHIBA, YOICHI SUZUKI, OSAMU TANABE, JUN YASUDA, FUMITOSHI SATO, MASATAKA KUDO, HIROSHI SATO,: "O-051 Examination of uremic substances that are drugally purified by oral alkalizing agents", 60TH ANNUAL MEETING OF THE JAPANESE SOCIETY OF NEPHROLOGY; MAY 26-28, 2017, 13 March 2017 (2017-03-13), JP, pages O-051, XP009531599
BRITO-ASHURST, I.D ET AL.: "Bicarbonate supplementation slows progression of CKD and improves nutritional status", J. AM. SOC. NEPHROL., vol. 20, 2009, pages 2075 - 2084, XP055673749, DOI: 10.1681/ASN.2008111205
SOUMA T. ET AL.: "Luminal alkalinization attenuates proteinuria-induced oxidative damage in proximal tubular cells", J. AM. SOC. NEPHROL., vol. 22, 2011, pages 635 - 648, XP055556938, DOI: 10.1681/ASN.2009111130
JOURNAL OF THE JAPANESE RENAL SOCIETY, 2012
JOURNAL OF THE JAPANESE SOCIETY OF NEPHROLOGY, 2012
See also references of EP 3964264A4
TOMOAKI ABE, DAISUKE SAEGUSA, SEIZO KOSHIBA, YOICHI SUZUKI, OSAMU TANABE, JUN YASUDA, FUMITOSHI SATO, MASATAKA KUDO, HIROSHI SATO,: "O-051 Examination of uremic substances that are drugally purified by oral alkalizing agents", 60TH ANNUAL MEETING OF THE JAPANESE SOCIETY OF NEPHROLOGY; MAY 26-28, 2017, 13 March 2017 (2017-03-13), JP, pages O-051, XP009531599
BRITO-ASHURST, I.D ET AL.: "Bicarbonate supplementation slows progression of CKD and improves nutritional status", J. AM. SOC. NEPHROL., vol. 20, 2009, pages 2075 - 2084, XP055673749, DOI: 10.1681/ASN.2008111205
SOUMA T. ET AL.: "Luminal alkalinization attenuates proteinuria-induced oxidative damage in proximal tubular cells", J. AM. SOC. NEPHROL., vol. 22, 2011, pages 635 - 648, XP055556938, DOI: 10.1681/ASN.2009111130
JOURNAL OF THE JAPANESE RENAL SOCIETY, 2012
JOURNAL OF THE JAPANESE SOCIETY OF NEPHROLOGY, 2012
See also references of EP 3964264A4
Attorney, Agent or Firm:
TANAI Sumio et al. (JP)
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