Title:
NOVEL PHARMACEUTICAL COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2023/149548
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing a novel pharmaceutical composition, and in particular, a novel anti-cancer pharmaceutical composition, and a novel compound used in said pharmaceutical composition. The present invention provides a pharmaceutical composition containing, as an active component, the compound represented by formula (I), or a pharmacologically acceptable salt thereof.
Inventors:
AWALE SURESH (JP)
TOYOOKA NAOKI (JP)
TOYOOKA NAOKI (JP)
Application Number:
PCT/JP2023/003580
Publication Date:
August 10, 2023
Filing Date:
February 03, 2023
Export Citation:
Assignee:
NATIONAL UNIV CORPORATION UNIV OF TOYAMA (JP)
International Classes:
A61K31/277; A61K31/167; A61K31/44; A61K31/4418; A61K31/536; A61P35/00; C07C235/56; C07C255/57; C07C255/60; C07D213/40; C07D213/75; C07D213/84; C07D265/26
Domestic Patent References:
| WO2019074747A1 | 2019-04-18 | |||
| WO2004022525A1 | 2004-03-18 |
Foreign References:
| JP2021536458A | 2021-12-27 | |||
| JP2011511806A | 2011-04-14 |
Other References:
KAUSHAL JYOTI, BHATIA RAKESH, KANCHAN RANJANA, RAUT PRATIMA, MALLAPRAGADA SURYA, LY QUAN, BATRA SURINDER, RACHAGANI SATYANARAYANA: "Repurposing Niclosamide for Targeting Pancreatic Cancer by Inhibiting Hh/Gli Non-Canonical Axis of Gsk3β", DEPARTMENT OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, UNIVERSITY OF NEBRASKA MEDICAL CENTER, OMAHA, NE 68198, USA, vol. 13, no. 13, pages 3105, XP093082542, DOI: 10.3390/cancers13133105
TANG, ZHONGHAI, ACUÑA, ULYANA MUÑOZ, FERNANDES, NELSON FREITAS, CHETTIAR, SOMSUNDARAM: "Structure–Activity Relationship of Niclosamide Derivatives", ANTICANCER RESEARCH, INTERNATIONAL INSTITUTE OF ANTICANCER RESEARCH, GR, vol. 37, no. 6, 29 May 2017 (2017-05-29), GR , pages 2839 - 2843, XP093082547, ISSN: 0250-7005, DOI: 10.21873/anticanres.11635
LI ZHONG, XU JIMIN, LANG YUEKUN, FAN XIAOYU, KUO LILI, D’BRANT LIANNA, HU SAIYANG, SAMRAT SUBODH KUMAR, TRUDEAU NICOLE, THARAPPEL : "JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo", ACS INFECTIOUS DISEASES, AMERICAN CHEMICAL SOCIETY, US, vol. 6, no. 10, 9 October 2020 (2020-10-09), US , pages 2616 - 2628, XP093082548, ISSN: 2373-8227, DOI: 10.1021/acsinfecdis.0c00217
TANG, ZHONGHAI, ACUÑA, ULYANA MUÑOZ, FERNANDES, NELSON FREITAS, CHETTIAR, SOMSUNDARAM: "Structure–Activity Relationship of Niclosamide Derivatives", ANTICANCER RESEARCH, INTERNATIONAL INSTITUTE OF ANTICANCER RESEARCH, GR, vol. 37, no. 6, 29 May 2017 (2017-05-29), GR , pages 2839 - 2843, XP093082547, ISSN: 0250-7005, DOI: 10.21873/anticanres.11635
LI ZHONG, XU JIMIN, LANG YUEKUN, FAN XIAOYU, KUO LILI, D’BRANT LIANNA, HU SAIYANG, SAMRAT SUBODH KUMAR, TRUDEAU NICOLE, THARAPPEL : "JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo", ACS INFECTIOUS DISEASES, AMERICAN CHEMICAL SOCIETY, US, vol. 6, no. 10, 9 October 2020 (2020-10-09), US , pages 2616 - 2628, XP093082548, ISSN: 2373-8227, DOI: 10.1021/acsinfecdis.0c00217
Attorney, Agent or Firm:
IP FIRM SHUWA (JP)
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