NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCE SULPHOSTIN, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF

Title:

NOVEL PHYSIOLOGICALLY ACTIVE SUBSTANCE SULPHOSTIN, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF

Document Type and Number:

WIPO Patent Application WO/1999/025719

Kind Code:

A1

Abstract:

A physiologically active substance, sulphostin, having a potent dipeptidylpeptidase IV inhibitory activity and obtained by culturing a microorganism belonging to the genus Streptomyces and capable of producing the above substance to accumulate the same in the culture medium and harvesting the same from the medium.

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Inventors:

TAKEUCHI TOMIO (JP)
HAMADA MASA (JP)
MURAOKA YASUHIKO (JP)
AKIYAMA TETSUO (JP)
ABE MASATOSHI (JP)
NAGANAWA HIROSHI (JP)
TAKAHASHI YOSHIKAZU (JP)

Application Number:

PCT/JP1998/005164

Publication Date:

May 27, 1999

Filing Date:

November 17, 1998

Export Citation:

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Assignee:

ZAIDAN HOJIN BISEIBUTSU (JP)
TAKEUCHI TOMIO (JP)
HAMADA MASA (JP)
MURAOKA YASUHIKO (JP)
AKIYAMA TETSUO (JP)
ABE MASATOSHI (JP)
NAGANAWA HIROSHI (JP)
TAKAHASHI YOSHIKAZU (JP)

International Classes:

A61K35/74; C07G99/00; C07K14/36; C12N9/99; C12P1/06; A61K38/00; (IPC1-7): C07G17/00; A61K35/74; C12N1/20; C12N9/99; C12P1/06

Domestic Patent References:

WO1997040832A1	1997-11-06
WO1995029691A1	1995-11-09
WO1995011689A1	1995-05-04
WO1994003055A1	1994-02-17

Other References: