Title:
NOVEL POLYNUCLEOTIDE AND UTILIZATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/088164
Kind Code:
A1
Abstract:
To provide a novel polynucleotide relating to APL and utilization thereof, one embodiment of the present invention pertains to a polynucleotide which encodes a fused polypeptide of a part or the full length of RARB with a part or the full length of TBL1XR1, or a polynucleotide which encodes a RARB mutant caused by translocation.
More Like This:
| WO/1997/044455 | HEMATOPOIETIC CYTOKINE RECEPTOR |
| WO/2020/159191 | COMPOSITION COMPRISING MLS-STAT3 FOR PREVENTION OR TREATMENT OF IMMUNE DISEASE |
| WO/2022/247795 | NANOBODY TARGETING CLAUDIN18.2 AND USE THEREOF |
Inventors:
KATO MOTOHIRO (JP)
OSUMI TMOO (JP)
KIYOKAWA NOBUTAKA (JP)
NAKABAYASHI KAZUHIKO (JP)
OSUMI TMOO (JP)
KIYOKAWA NOBUTAKA (JP)
NAKABAYASHI KAZUHIKO (JP)
Application Number:
PCT/JP2018/040494
Publication Date:
May 09, 2019
Filing Date:
October 31, 2018
Export Citation:
Assignee:
NAT CT CHILD HEALTH & DEV (JP)
International Classes:
C12N15/62; A61K31/07; A61P35/02; C07K14/705; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/12; C12Q1/68; C12Q1/6886; G01N33/68
Other References:
KIYOI, HITOSHI: "(non-official translation) Treatment of Acute promyelocytic leukemia", THE JOURNAL OF THE JAPANESE SOCIETY OF INTERNAL MEDICINE, vol. 102, no. 7, pages 1705 - 1711, ISSN: 0021-5384
FREY J. R. ET AL.: "Antiproliferative activity of retinoids, interferon a and their combination in five human transformed cell lines", CANCER LETTERS, vol. 57, 1991, pages 223 - 227, XP026183387, ISSN: 0304-3835, DOI: doi:10.1016/0304-3835(91)90161-A
OSUMI T. ET AL.: "Recurrent RARB Translocations in Acute Promyelocytic Leukemia Lacking RARA Translocation", CANCER RESEARCH, vol. 78, no. 16, 19 June 2018 (2018-06-19), pages 4452 - 4458, XP055613653, ISSN: 0008-5472, DOI: 10.1158/0008-5472.CAN-18-0840
FREY J. R. ET AL.: "Antiproliferative activity of retinoids, interferon a and their combination in five human transformed cell lines", CANCER LETTERS, vol. 57, 1991, pages 223 - 227, XP026183387, ISSN: 0304-3835, DOI: doi:10.1016/0304-3835(91)90161-A
OSUMI T. ET AL.: "Recurrent RARB Translocations in Acute Promyelocytic Leukemia Lacking RARA Translocation", CANCER RESEARCH, vol. 78, no. 16, 19 June 2018 (2018-06-19), pages 4452 - 4458, XP055613653, ISSN: 0008-5472, DOI: 10.1158/0008-5472.CAN-18-0840
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (JP)
Download PDF: