Title:
NOVEL PRMT5 INHIBITOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/067433
Kind Code:
A1
Abstract:
The present invention describes a novel molecule with inhibitory activity against protein arginine methyltransferase 5 and methods for synthesis and use of the compound. Specifically, the present invention describes a compound of formula (I) or a pharmaceutically acceptable salt thereof, a hydrate therof, or a solvate thereof, and methods for synthesis and use of the compound.
Inventors:
YAO BING (CN)
GU XIAOHUI (CN)
GU XIAOHUI (CN)
Application Number:
PCT/CN2023/120923
Publication Date:
April 04, 2024
Filing Date:
September 25, 2023
Export Citation:
Assignee:
SHANGHAI APEIRON THERAPEUTICS COMPANY LTD (CN)
International Classes:
C07D471/14; A61K31/519; A61K31/536; A61P35/00; C07D487/04; C07D519/00
Domestic Patent References:
| WO2021254493A1 | 2021-12-23 | |||
| WO2004085439A1 | 2004-10-07 | |||
| WO2021254529A1 | 2021-12-23 | |||
| WO2022048631A1 | 2022-03-10 |
Foreign References:
| CN102388044A | 2012-03-21 | |||
| CN113234079A | 2021-08-10 |
Attorney, Agent or Firm:
UNITALEN ATTORNEYS AT LAW CO., LTD. (CN)
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