Title:
NOVEL PYRIMIDO[4,5-D]PYRIMIDINE-2-ONE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY
Document Type and Number:
WIPO Patent Application WO/2021/040422
Kind Code:
A1
Abstract:
The present invention relates to: a pyrimido[4,5-d]pyrimidine-2-one derivative compound exhibiting excellent anti-proliferative effects on cancer cells, a pharmaceutically acceptable salt thereof, a hydrate thereof, or a stereoisomer thereof; a preparation method therefor; a pharmaceutical composition for preventing, alleviating, or treating cancer metastasis and proliferative diseases, containing same as an active ingredient; and an anti-cancer composition used on cancer cells, wherein the compound exhibits excellent cancer cell inhibitory activities and anti-proliferative effects, thereby being useful in the inhibition of cancer cells and, further, in the prevention of cancer metastasis and proliferative diseases or in cancer treatment.
Inventors:
HAN SEO JUNG (KR)
SIM TAE BO (KR)
OH DO HEE (KR)
CHEONG JAE EUN (KR)
HWANG DONG KEON (KR)
SIM TAE BO (KR)
OH DO HEE (KR)
CHEONG JAE EUN (KR)
HWANG DONG KEON (KR)
Application Number:
PCT/KR2020/011455
Publication Date:
March 04, 2021
Filing Date:
August 27, 2020
Export Citation:
Assignee:
KOREA INST SCI & TECH (KR)
International Classes:
C07D487/04; A61K31/513; A61K31/551; A61P29/00; A61P35/00; A61P37/00
Domestic Patent References:
WO2005011597A2 | 2005-02-10 | |||
WO1996034867A1 | 1996-11-07 | |||
WO2019091476A1 | 2019-05-16 | |||
WO2012167415A1 | 2012-12-13 |
Foreign References:
EP3048099A2 | 2016-07-27 | |||
US8058283B2 | 2011-11-15 |
Attorney, Agent or Firm:
HALLA PATENT & LAW FIRM (KR)
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