NOVEL SULFONAMIDE DERIVATIVE

Title:

NOVEL SULFONAMIDE DERIVATIVE

Document Type and Number:

WIPO Patent Application WO/2005/097738

Kind Code:

A1

Abstract:

Disclosed are a compound represented by the formula (1) below, a prodrug thereof, and their pharmaceutically acceptable salts which have an effect of increasing LDL receptor expression and are useful as drugs for treating hyperlipemia, arteriosclerosis and the like. (1) (In the formula, m, n and p independently represent an integer of 0-4 and 3 ≤ m + n ≤ 8; X represents a group expressed as NR⁴ or the like; R¹, R³ and R⁴ represent a substituted or unsubstituted aryl group or the like; R² represents a hydrogen atom or the like; a, b, c, d, e and f respectively represent a hydrogen atom, a substituted or unsubstituted alkyl group or the like; Y represents -SO₂- or the like; and Z represents an oxygen atom or the like.)

Inventors:

BAN HITOSHI (JP)
ASANO SHIGEHIRO (JP)

Application Number:

PCT/JP2005/006977

Publication Date:

October 20, 2005

Filing Date:

April 04, 2005

Export Citation:

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Assignee:

SUMITOMO PHARMA (JP)
BAN HITOSHI (JP)
ASANO SHIGEHIRO (JP)

International Classes:

A61K31/255; A61K31/44; A61K31/454; A61K31/506; A61K31/55; A61K31/664; A61P3/06; A61P9/10; A61P43/00; C07C307/02; C07C307/06; C07C311/05; C07C311/18; C07C311/37; C07C317/32; C07D211/34; C07D211/58; C07D211/60; C07D211/64; C07D211/70; C07D211/72; C07D213/06; C07D223/06; C07D401/04; C07D413/04; C07D417/04; C07D451/02; C07F9/59; (IPC1-7): C07C307/02; A61K31/255; A61K31/44; A61K31/454; A61K31/506; A61K31/55; A61K31/664; A61P3/06; A61P9/10; A61P43/00; C07C307/06; C07C311/05; C07C311/18; C07C317/32; C07D211/64; C07D213/06; C07D223/06; C07D401/04; C07D413/04; C07D417/04; C07F9/59

Domestic Patent References:

WO2003091216A1	2003-11-06
WO2003059871A1	2003-07-24

Foreign References:

JP2003055326A	2003-02-26
JP2004506037A	2004-02-26

Other References: