Title:
NOVEL TETRA-AZA MACROCYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2011/031073
Kind Code:
A2
Abstract:
The present invention relates to a cross-linked tetra-aza macrocyclic compound which has a novel structure and which can be used as a contrast agent for diagnostic images, radiopharmaceuticals, and the like, and relates to a method for preparing same. As compared to conventional cross-linked tetra-aza macrocyclic compounds, the tetra-aza macrocyclic compound of the present invention is advantageous in that the compound of the present invention forms a stable metal complex at a lower temperature and can be easily conjugated with biologically active materials and chemically active materials.
Inventors:
YOO JEONG SOO (KR)
PANDYA DARPAN (KR)
PANDYA DARPAN (KR)
Application Number:
PCT/KR2010/006139
Publication Date:
March 17, 2011
Filing Date:
September 09, 2010
Export Citation:
Assignee:
KYUNGPOOK NAT UNIV IND ACAD (KR)
YOO JEONG SOO (KR)
PANDYA DARPAN (KR)
YOO JEONG SOO (KR)
PANDYA DARPAN (KR)
International Classes:
C07D487/04; A61K49/04; A61P31/00; A61P35/00; C07D257/02; C07D403/12
Domestic Patent References:
| WO2002026267A2 | 2002-04-04 |
Foreign References:
| US6916460B2 | 2005-07-12 | |||
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Other References:
J. AM. CHEM. SOC., vol. 122, 2000, pages 10561 - 10572
"Chemotherapy Source Book", WILLIAMS & WILKENS PUBLISHING
See also references of EP 2476683A4
"Chemotherapy Source Book", WILLIAMS & WILKENS PUBLISHING
See also references of EP 2476683A4
Attorney, Agent or Firm:
J.C.HYUN PATENT & LAW FIRM (353-18 Shindang 2-dong, Jung-gu, Seoul 100-828, KR)
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