Title:
NOVEL TETRAHYDRODIPICOLINATE N-SUCCINYLTRANSFERASE VARIANT, AND METHOD FOR PRODUCING L-VALINE USING SAME
Document Type and Number:
WIPO Patent Application WO/2022/163918
Kind Code:
A1
Abstract:
The present application relates to a novel tetrahydrodipicolinate N-succinyltransferase variant, a Corynebacterium glutamicum strain comprising the variant, and a method for producing L-valine using the strain.
Inventors:
BAE JEE YEON (KR)
KIM SEON HYE (KR)
YOON BYOUNG HOON (KR)
PARK GOUN (KR)
KIM HYO JIN (KR)
KIM HYUNG JOON (KR)
KIM SEON HYE (KR)
YOON BYOUNG HOON (KR)
PARK GOUN (KR)
KIM HYO JIN (KR)
KIM HYUNG JOON (KR)
Application Number:
PCT/KR2021/004510
Publication Date:
August 04, 2022
Filing Date:
April 09, 2021
Export Citation:
Assignee:
CJ CHEILJEDANG CORP (KR)
International Classes:
C12N9/10; C12N15/77; C12P13/08
Foreign References:
| KR101117022B1 | 2012-03-16 | |||
| KR20130070302A | 2013-06-27 | |||
| KR20200026881A | 2020-03-11 | |||
| KR101721722B1 | 2017-04-10 | |||
| US8465962B2 | 2013-06-18 | |||
| US7662943B2 | 2010-02-16 | |||
| US10584338B2 | 2020-03-10 | |||
| US10273491B2 | 2019-04-30 |
Other References:
DATABASE Protein 22 December 2016 (2016-12-22), "succinyltransferase [Corynebacterium glutamicum]", XP055945539, retrieved from NCBI Database accession no. WP_074506321.1
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL.: "EMBOSS: The European Molecular Biology Open Software Suite", TRENDS GENET., vol. 16, 2000, pages 276 - 277, XP004200114, DOI: 10.1016/S0168-9525(00)02024-2
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
GENE, vol. 145, 1994, pages 69 - 73
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"Atlas Of Protein Sequence And Structure", 1979, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, pages: 353 - 358
RICE ET AL.: "EMBOSS: The European Molecular Biology Open Software Suite", TRENDS GENET, vol. 16, 2000, pages 276 - 277, XP004200114, DOI: 10.1016/S0168-9525(00)02024-2
J. SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
NAKASHIMA N. ET AL.: "Bacterial cellular engineering by genome editing and gene silencing", INT J MOL SCI., vol. 15, no. 2, 2014, pages 2773 - 2793, XP055376889, DOI: 10.3390/ijms15022773
WEINTRAUB, H. ET AL.: "Antisense-RNA as a molecular tool for genetic analysis", REVIEWS-TRENDS IN GENETICS, vol. 1, no. 1, 1986
SITNICKA ET AL.: "Functional Analysis of Genes", ADVANCES IN CELL BIOLOGY, vol. 2, 2010, pages 1 - 16
SAMBROOK ET AL., MOLECULAR CLONING, 2012
"Manual of Methods for General Bacteriology", 1981, AMERICAN SOCIETY FOR BACTERIOLOGY
See also references of EP 4060030A4
PEARSON ET AL., PROC. NATL. ACAD. SCI. USA, vol. 85, 1988, pages 2444
NEEDLEMANWUNSCH, J. MOL. BIOL., vol. 48, 1970, pages 443 - 453
RICE ET AL.: "EMBOSS: The European Molecular Biology Open Software Suite", TRENDS GENET., vol. 16, 2000, pages 276 - 277, XP004200114, DOI: 10.1016/S0168-9525(00)02024-2
DEVEREUX, J. ET AL., NUCLEIC ACIDS RESEARCH, vol. 12, 1984, pages 387
ATSCHUL, S. F. ET AL., J MOLEC BIOL, vol. 215, 1990, pages 403
GENE, vol. 145, 1994, pages 69 - 73
CARILLO ET AL., SIAM J APPLIED MATH, vol. 48, 1988, pages 1073
NEEDLEMAN ET AL., J MOL BIOL., vol. 48, 1970, pages 443
SMITHWATERMAN, ADV. APPL. MATH, vol. 2, 1981, pages 482
GRIBSKOV ET AL., NUCL. ACIDS RES., vol. 14, 1986, pages 6745
"Atlas Of Protein Sequence And Structure", 1979, NATIONAL BIOMEDICAL RESEARCH FOUNDATION, pages: 353 - 358
RICE ET AL.: "EMBOSS: The European Molecular Biology Open Software Suite", TRENDS GENET, vol. 16, 2000, pages 276 - 277, XP004200114, DOI: 10.1016/S0168-9525(00)02024-2
J. SAMBROOK ET AL.: "Molecular Cloning, A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
NAKASHIMA N. ET AL.: "Bacterial cellular engineering by genome editing and gene silencing", INT J MOL SCI., vol. 15, no. 2, 2014, pages 2773 - 2793, XP055376889, DOI: 10.3390/ijms15022773
WEINTRAUB, H. ET AL.: "Antisense-RNA as a molecular tool for genetic analysis", REVIEWS-TRENDS IN GENETICS, vol. 1, no. 1, 1986
SITNICKA ET AL.: "Functional Analysis of Genes", ADVANCES IN CELL BIOLOGY, vol. 2, 2010, pages 1 - 16
SAMBROOK ET AL., MOLECULAR CLONING, 2012
"Manual of Methods for General Bacteriology", 1981, AMERICAN SOCIETY FOR BACTERIOLOGY
See also references of EP 4060030A4
Attorney, Agent or Firm:
YOU ME PATENT AND LAW FIRM (KR)
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