NOVEL TRITERPENIC ACID DERIVATIVE AND PREPARATION FOR EXTERNAL APPLICATION FOR SKIN COMPRISING THE SAME

Title:

NOVEL TRITERPENIC ACID DERIVATIVE AND PREPARATION FOR EXTERNAL APPLICATION FOR SKIN COMPRISING THE SAME

Document Type and Number:

WIPO Patent Application WO/2006/132033

Kind Code:

A1

Abstract:

In a triterpenic acid having hydroxyl groups, at least one of the hydroxyl groups is phosphatized to produce a phosphatized triterpenic acid and/or a salt thereof, thereby improving the solubility of the triterpenic acid in a preparation for external application for the skin and allowing the physiological activity of the triterpenic acid to be exerted satisfactorily. The phosphatized triterpenic acid is preferably, for example, ursolic acid phosphate and/or a salt thereof. The preparation for external application for the skin is preferably a cosmetic, particularly preferably a medicated cosmetic.

Inventors:

OCHIAI MICHIO (JP)
GOTO KENICHI (JP)
TOKUDOME YOSHIHIRO (JP)
HIROKAWA SHIGENARI (JP)

Application Number:

PCT/JP2006/307818

Publication Date:

December 14, 2006

Filing Date:

April 13, 2006

Export Citation:

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Assignee:

POLA CHEM IND INC (JP)
OCHIAI MICHIO (JP)
GOTO KENICHI (JP)
TOKUDOME YOSHIHIRO (JP)
HIROKAWA SHIGENARI (JP)

International Classes:

C07J63/00; A61K8/55; A61K31/661; A61P17/16; A61Q19/02

Domestic Patent References:

WO2004047792A2	2004-06-10
WO2001072265A1	2001-10-04
WO2001017523A1	2001-03-15

Foreign References:

JPH1112122A	1999-01-19
JP2004131403A	2004-04-30
JPH06505702A	1994-06-30
JP2000302659A	2000-10-31
JP2004331593A	2004-11-25
JPH08165231A	1996-06-25
JPH08208424A	1996-08-13
JPS6472265A	1989-03-17
JPH1112122A	1999-01-19
JP2000302659A	2000-10-31
JP2004331593A	2004-11-25
JPH11158197A	1999-06-15
JP2001354513A	2001-12-25
US3454613A	1969-07-08

Other References: