NOVEL USE OF LACTOBACILLUS DELBRUECKII SUBSP. LACTIS STRAIN

Title:

NOVEL USE OF LACTOBACILLUS DELBRUECKII SUBSP. LACTIS STRAIN

Document Type and Number:

WIPO Patent Application WO/2024/096644

Kind Code:

A1

Abstract:

The present invention relates to a composition for preventing, alleviating or treating cognitive impairment or Alzheimer's disease, comprising a Lactobacillus delbrueckii subsp. lactis strain as an active ingredient. The present invention provides a composition for preventing, alleviating or treating cognitive impairment or Alzheimer's disease (AD), comprising a Lactobacillus delbrueckii subsp. lactis strain as an active ingredient. The strain of the present invention has the excellent effects of reducing amyloid beta protein (Aβ) or tau protein (Tau) and improving cognitive function, and thus can be effectively used as a composition for preventing, alleviating or treating cognitive impairment or AD.

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Inventors:

NOH HYE-JI (KR)
CHA LINA (KR)
LEE IN OCK (KR)
MOOK INHEE (KR)
CHOI HYUNJUNG (KR)
KIM KYUNG HWAN (KR)
KIM BYOUNG-KOOK (KR)
SHIN CHANG-HUN (KR)
KIM HYERIM (KR)
KIM HYEYOUNG (KR)
LEE SURO (KR)
LEE HYERIM (KR)
HONG RIWON (KR)
HEO JINAH (KR)

Application Number:

PCT/KR2023/017436

Publication Date:

May 10, 2024

Filing Date:

November 02, 2023

Export Citation:

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Assignee:

CKD BIO CORP (KR)
GENOME & COMPANY (KR)

International Classes:

A61K35/747; A23L33/135; A61P25/28

Foreign References:

JP7057039B2	2022-04-19
KR101937758B1	2019-01-11
KR101087972B1	2011-12-01
US20200197447A1	2020-06-25

Other References:

SEDA SIRIN: "Characterization of lactic acid bacteria derived exopolysaccharides for use as a defined neuroprotective agent against amyloid beta1–42-induced apoptosis in SH-SY5Y cells", SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, US, vol. 10, no. 1, 1 January 2020 (2020-01-01), US , XP093166996, ISSN: 2045-2322, DOI: 10.1038/s41598-020-65147-1

Attorney, Agent or Firm:

IPSCENT (KR)

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