NOVEL USE OF SULFAMIC ACIDS AS RESOLVING AGENT.

WIPO Patent Application WO2002100804

A3

The invention relates to the use of chiral sulfamic acids as resolving agents, the sulfamic acid having the formula (R1, R2) N-SO3H, wherein: R1 and R2, being the same or different, represent a hydrogen atom or a C1-C30 linear, branched or cyclic (hetero)-aliphatic or (hetero)-aromatic group, provided that R1 and R2 are not both hydrogen and that at least one of the R1 and R2 groups is chiral. Further, methods for resolving enantiomeric mixtures are disclosed.

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SMITH ALAN ARTHUR (NL)
DAMEN FRANCISCUS WILHELMUS PET (NL)
KUSTER GEORGE JOHANNES THEODOR (NL)

PCT/EP2002/006321

May 08, 2003

June 07, 2002

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AVANTIUM INT BV (NL)
SMITH ALAN ARTHUR (NL)
DAMEN FRANCISCUS WILHELMUS PET (NL)
KUSTER GEORGE JOHANNES THEODOR (NL)

C07B57/00; C07C307/02; (IPC1-7): C07B57/00; C07C307/02

US4582928A

1986-04-15

K.B. WIBERG: "Organic Syntheses, vol. 49", 1969, JOHN WILEY AND SONS, NEW YORK, NY, US, XP002182283
A.H. BLATT: "Organic Syntheses, Collective Volume 2", 1946, JOHN WILEY AND SONS, NEW YORK, NY, US, XP002182284

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