Title:
NPYY5 ANTAGONISTS
Document Type and Number:
WIPO Patent Application WO/2001/037826
Kind Code:
A1
Abstract:
NPYY5 receptor antagonists which contain compounds represented bygeneral formula (I), prodrugs thereof, pharmaceutically acceptable salts thereof or solvates of the same wherein R?1¿ represents lower alkyl, cycloalkyl, etc.; R?2¿ represents hydrogen, lower alkyl, etc.; n is 1 or 2; X represents lower alkylene, lower alkenylene, arylene, cycloalkylene, etc.; Y represents CONR?7¿, CSNR?7¿, NR?7¿CO, NR?7¿CS, etc. (wherein R?7¿ represents hydrogen or lower alkyl); and Z represents lower alkyl, an optionally substituted hydrocarbon cycle, an optionally substituted heterocycle, etc.
Inventors:
KAWANISHI YASUYUKI (JP)
TAKENAKA HIDEYUKI (JP)
HANASAKI KOHJI (JP)
OKADA TETSUO (JP)
TAKENAKA HIDEYUKI (JP)
HANASAKI KOHJI (JP)
OKADA TETSUO (JP)
Application Number:
PCT/JP2000/008197
Publication Date:
May 31, 2001
Filing Date:
November 21, 2000
Export Citation:
Assignee:
SHIONOGI & CO (JP)
KAWANISHI YASUYUKI (JP)
TAKENAKA HIDEYUKI (JP)
HANASAKI KOHJI (JP)
OKADA TETSUO (JP)
KAWANISHI YASUYUKI (JP)
TAKENAKA HIDEYUKI (JP)
HANASAKI KOHJI (JP)
OKADA TETSUO (JP)
International Classes:
A61K31/00; A61K31/18; A61K31/341; A61K31/351; A61K31/357; A61K31/37; A61K31/381; A61K31/4015; A61K31/402; A61K31/4035; A61K31/41; A61K31/415; A61K31/4196; A61K31/42; A61K31/421; A61K31/423; A61K31/425; A61K31/428; A61K31/433; A61K31/44; A61K31/4409; A61K31/4453; A61K31/451; A61K31/495; A61K31/4965; A61K31/505; A61K31/535; A61K31/5375; A61K31/63; A61K31/635; A61P3/04; A61P43/00; C07C311/06; C07C311/07; C07C311/08; C07C311/14; C07C311/20; C07C311/21; C07C311/46; C07C323/40; C07D207/09; C07D207/12; C07D207/16; C07D209/08; C07D209/48; C07D209/88; C07D211/08; C07D211/58; C07D211/62; C07D213/75; C07D213/82; C07D215/36; C07D215/38; C07D217/04; C07D219/10; C07D231/12; C07D231/16; C07D231/56; C07D233/68; C07D239/42; C07D241/02; C07D261/08; C07D265/30; C07D277/46; C07D277/56; C07D277/70; C07D285/06; C07D295/135; C07D307/02; C07D307/68; C07D307/91; C07D311/16; C07D317/66; C07D333/38; C07D333/72; C07D521/00; A61K; A61P; C07C; C07D; (IPC1-7): A61K31/18; A61K31/5375; A61K31/381; A61K31/343; A61K31/445; A61K31/4035; A61K31/472; A61K31/4164; A61K31/36; A61K31/505; A61K31/37; A61K31/40; A61K31/415; A61K31/433; A61K31/495; A61K31/426; A61K31/4409; A61K31/428; A61K31/47; A61K31/423; A61K31/421; A61K31/42; A61K31/416; A61K31/5377; A61K31/506; A61K31/454; A61K31/4525; A61K31/4535; A61K31/453; A61K31/357; A61K31/353; A61K31/351; A61K31/216; A61K31/27; A61K31/275; A61K31/196; A61P43/00; A61P3/04; C07D265/30; C07D333/38; C07D307/68; C07D211/58; C07D209/48; C07D209/88; C07D211/62; C07D211/70; C07D217/40; C07D207/335; C07D233/68; C07D317/66; C07D211/26; C07D239/42; C07D311/18; C07D207/14; C07D209/08; C07D231/12; C07D207/16; C07D285/06; C07D257/04; C07D277/46; C07D295/12; C07D207/12; C07D213/40; C07D277/72; C07D307/91; C07D215/38; C07D263/56; C07D263/32; C07D261/08; C07D231/56; C07D33/54; C07D333/20; C07D413/04; C07D413/12; C07D401/12; C07D409/12; C07D405/12; C07D417/12; C07D215/36; C07D319/18; C07D285/12; C07D311/58; C07D309/12; C07D309/10; C07D309/04; C07D309/06; C07D285/14; C07C311/06; C07C311/07; C07C311/08; C07C311/09; C07C311/42; C07C311/46
Domestic Patent References:
| WO2001002379A1 | 2001-01-11 | |||
| WO2000063171A1 | 2000-10-26 | |||
| WO1999032466A1 | 1999-07-01 | |||
| WO1997020820A1 | 1997-06-12 | |||
| WO1997020821A1 | 1997-06-12 | |||
| WO1997020823A2 | 1997-06-12 |
Foreign References:
| EP1010691A2 | 2000-06-21 | |||
| EP0148725A1 | 1985-07-17 | |||
| JPS5916871A | 1984-01-28 |
Other References:
See also references of EP 1249233A4
Attorney, Agent or Firm:
Yamauchi, Hideaki (Ltd. Intellectual Property Department 12-4
Sagisu 5-chom, Fukushima-ku Osaka-shi Osaka, JP)
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