Title:
NUCLEIC ACID CONSTRUCT FOR GENE EDITING
Document Type and Number:
WIPO Patent Application WO/2020/177751
Kind Code:
A1
Abstract:
Provided is a nucleic acid construct for gene editing, wherein the nucleic acid construct having a specific structure can permit gRNA-directed site-directed mutagenesis of bases in plants.
Inventors:
LI FENG (CN)
LIANG YAFENG (CN)
LIANG YAFENG (CN)
Application Number:
PCT/CN2020/078079
Publication Date:
September 10, 2020
Filing Date:
March 05, 2020
Export Citation:
Assignee:
SHANDONG SHUNFENG BIOTECHNOLOGY CO LTD (CN)
International Classes:
C12N15/82; A01H5/00; A01H6/20; A01H6/46; A01H6/54; C07K19/00; C12N5/10; C12N9/22; C12N9/78
Foreign References:
| CN110526993A | 2019-12-03 | |||
| CN110527695A | 2019-12-03 | |||
| CN110157726A | 2019-08-23 | |||
| CN106609282A | 2017-05-03 | |||
| CN104293828A | 2015-01-21 |
Other References:
KAI HUA: "Precise A.T to G*C Base Editing in the Rice Genome", MOLECULAR PLANT, vol. 11, no. 4, 21 February 2018 (2018-02-21), pages 627 - 630, XP055655070, ISSN: 1752-9867
ZAFRA MARIA PAZ, SCHATOFF EMMA M, KATTI ALYNA, FORONDA MIGUEL, BREINIG MARCO, SCHWEITZER ANABEL Y, SIMON AMBER, HAN TENG, GOSWAMI : "Optimized Base Editors Enable Efficient Editing in Cells, Organoids and Mice", NAT BIOTECHNOL., vol. 36, no. 9, 3 July 2018 (2018-07-03), pages 888 - 893, XP036929662, ISSN: 1546-1696
ZAFRA MARIA PAZ, SCHATOFF EMMA M, KATTI ALYNA, FORONDA MIGUEL, BREINIG MARCO, SCHWEITZER ANABEL Y, SIMON AMBER, HAN TENG, GOSWAMI : "Optimized Base Editors Enable Efficient Editing in Cells, Organoids and Mice", NAT BIOTECHNOL., vol. 36, no. 9, 3 July 2018 (2018-07-03), pages 888 - 893, XP036929662, ISSN: 1546-1696
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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