NUCLEIC ACID MOLECULE CAPABLE OF BLOCKING MOTOR PROTEIN, AND CONSTRUCTION METHOD AND APPLICATION THEREOF

Title:

NUCLEIC ACID MOLECULE CAPABLE OF BLOCKING MOTOR PROTEIN, AND CONSTRUCTION METHOD AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2023/123344

Kind Code:

A1

Abstract:

The present invention relates to a nucleic acid molecule capable of blocking a motor protein, a library containing the nucleic acid molecule, a method for constructing the nucleic acid molecule or library containing same, and an application of the nucleic acid molecule or library containing same. The nucleic acid molecule contains at the end a modified nucleotide capable of blocking a motor protein, and the modified nucleotide is as shown in Formula (I) or Formula (I'):

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Inventors:

WANG OU (CN)
SHI XIAO (CN)
XU XUN (CN)
ZHANG WENWEI (CN)
GUO FEI (CN)
BAO SIYU (CN)
DONG YULIANG (CN)
ZENG TAO (CN)

Application Number:

PCT/CN2021/143658

Publication Date:

July 06, 2023

Filing Date:

December 31, 2021

Export Citation:

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Assignee:

BGI SHENZHEN (CN)

International Classes:

C12N15/113; C12Q1/6806; C12Q1/6869; C40B40/06

Domestic Patent References:

WO2021255476A2	2021-12-23
WO2021099801A1	2021-05-27

Foreign References:

CN113736778A	2021-12-03
US20130303385A1	2013-11-14
US20190352709A1	2019-11-21
CN111154845A	2020-05-15
CN113025697A	2021-06-25

Attorney, Agent or Firm:

CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)

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