Title:
NUCLEIC ACID SEQUENCES ENCODING LUCIFERASE FOR EXPRESSION IN FILAMENTOUS FUNGI
Document Type and Number:
WIPO Patent Application WO2006049777
Kind Code:
A3
Abstract:
The present invention relates to genetic reporters. Specifically, the present invention is directed to a modified gene encoding a luciferase for high level expression in an organism with a bias for cytosine (C) or guanine (G) in the third position of the codon.
Inventors:
DUNLAP JAY C (US)
LOROS JENNIFER J (US)
MEHRA ARUN (US)
GOOCH VAN D (US)
LOROS JENNIFER J (US)
MEHRA ARUN (US)
GOOCH VAN D (US)
Application Number:
PCT/US2005/035325
Publication Date:
August 10, 2006
Filing Date:
September 30, 2005
Export Citation:
Assignee:
DARTMOUTH COLLEGE (US)
UNIV MINNESOTA (US)
DUNLAP JAY C (US)
LOROS JENNIFER J (US)
MEHRA ARUN (US)
GOOCH VAN D (US)
UNIV MINNESOTA (US)
DUNLAP JAY C (US)
LOROS JENNIFER J (US)
MEHRA ARUN (US)
GOOCH VAN D (US)
International Classes:
C12N9/02; A01N1/00; C12N15/00; G01N33/53
Foreign References:
| US5795737A | 1998-08-18 | |||
| US5837458A | 1998-11-17 | |||
| US5811238A | 1998-09-22 |
Other References:
FOURRIER ET AL.: "Simple, powerful promoter and enhancer analysis with MightyLight System", INNOVATIONS, vol. 16, March 2003 (2003-03-01), pages 13 - 16, XP008071375
BUDISA ET AL.: "Toward the experimental codon reassignment in vivo: protein building with an expanded amino acid repertoire", FASEB, vol. 13, January 1999 (1999-01-01), pages 41 - 51, XP003002646
CAMPBELL W.H. ET AL.: "Codon usage in higher plants, green algae, and Cyanobacteria", PLANT PHYSIOL., vol. 92, 1990, pages 1 - 11, XP002095344
FRANKLIN ET AL.: "Development of a GFP reporter gene for Chlamydomonas reinhardtii chloroplast", THE PLANT JOURNAL, vol. 30, no. 6, 2002, pages 733 - 744, XP003002647
SATYA R.V. ET AL.: "A pattern matching algorithm for codon optimization and CpG motif-engineering in DNA expression vectors", BIOINFORMATICS CONFERENCE, 2003. CSB 2003. PROCEEDINGS OF THE 2003, 11 August 2003 (2003-08-11), pages 294 - 305, XP010656406
BUDISA ET AL.: "Toward the experimental codon reassignment in vivo: protein building with an expanded amino acid repertoire", FASEB, vol. 13, January 1999 (1999-01-01), pages 41 - 51, XP003002646
CAMPBELL W.H. ET AL.: "Codon usage in higher plants, green algae, and Cyanobacteria", PLANT PHYSIOL., vol. 92, 1990, pages 1 - 11, XP002095344
FRANKLIN ET AL.: "Development of a GFP reporter gene for Chlamydomonas reinhardtii chloroplast", THE PLANT JOURNAL, vol. 30, no. 6, 2002, pages 733 - 744, XP003002647
SATYA R.V. ET AL.: "A pattern matching algorithm for codon optimization and CpG motif-engineering in DNA expression vectors", BIOINFORMATICS CONFERENCE, 2003. CSB 2003. PROCEEDINGS OF THE 2003, 11 August 2003 (2003-08-11), pages 294 - 305, XP010656406
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