Title:
NUCLEOTIDE ANALOGUE FOR SEQUENCING
Document Type and Number:
WIPO Patent Application WO/2022/206922
Kind Code:
A1
Abstract:
The present invention relates to the field of nucleic acid sequencing. Specifically, provided in the present invention is a nucleotide analogue for sequencing. The nucleotide analogue carries a linker on the base or the ribose ring 3'-OH, and can be used for NGS sequencing. The present invention further relates to a kit containing the nucleotide analogue, and a sequencing method based on the nucleotide analogue.
Inventors:
XU XUN (CN)
TENG BO (CN)
ZHANG WENWEI (CN)
SHEN LIANG (CN)
ZHUO SHITIAN (CN)
YAN SHENGYI (CN)
GAO NANFENG (CN)
ZHANG YONGHUI (CN)
ZHAO JIE (CN)
LIAO SHA (CN)
WANG MING (CN)
ZHANG SHAOQIAO (CN)
CHEN AO (CN)
LI HANDONG (CN)
TENG BO (CN)
ZHANG WENWEI (CN)
SHEN LIANG (CN)
ZHUO SHITIAN (CN)
YAN SHENGYI (CN)
GAO NANFENG (CN)
ZHANG YONGHUI (CN)
ZHAO JIE (CN)
LIAO SHA (CN)
WANG MING (CN)
ZHANG SHAOQIAO (CN)
CHEN AO (CN)
LI HANDONG (CN)
Application Number:
PCT/CN2022/084601
Publication Date:
October 06, 2022
Filing Date:
March 31, 2022
Export Citation:
Assignee:
BGI SHENZHEN (CN)
MGI HOLDINGS CO LTD (CN)
MGI HOLDINGS CO LTD (CN)
International Classes:
C07H19/10; A61K31/70; A61K31/7042; A61K31/7052; C07H21/00; C07H21/04; C12Q1/68
Domestic Patent References:
| WO2019071474A1 | 2019-04-18 | |||
| WO2009051807A1 | 2009-04-23 | |||
| WO2022083686A1 | 2022-04-28 | |||
| WO2018129214A1 | 2018-07-12 |
Foreign References:
| CN108779138A | 2018-11-09 | |||
| CN109661232A | 2019-04-19 | |||
| CN112218640A | 2021-01-12 | |||
| US20180223358A1 | 2018-08-09 | |||
| CN2021125262W | 2021-10-21 |
Other References:
SHOSHANI ILANA, QIU HOWARD, JOHNSON FRANCIS, JOHNSON ROGER A.: "Synthesis of Iodo-aryl-azido Adenosine Analogs as Affinity Ligands for Adenylyl Cyclase", NUCLEOSIDES AND NUCLEOTIDES, TAYLOR & FRANCIS, US, vol. 13, no. 9, 1 September 1994 (1994-09-01), US , pages 1977 - 1989, XP009535854, ISSN: 0732-8311, DOI: 10.1080/15257779408010676
J. SAMBROOK ET AL.: "Molecular Cloning: A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
F.M. AUSUBEL ET AL.: "Short Protocols in Molecular Biology", 1995, JOHN WILEY&SONS, INC.
WELCH ET AL., CHEM. EUR. J., vol. 5, no. 3, 1999, pages 951 - 960
ZHU ET AL., CYTOMETRY, vol. 28, 1997, pages 206 - 211
PROBER ET AL., SCIENCE, vol. 238, 1987, pages 336 - 341
CONNELL ET AL., BIOTECHNIQUES, vol. 5, no. 4, 1987, pages 342 - 384
ANSORGE ET AL., NUCL. ACIDS RES., vol. 15, no. 11, 1987, pages 4593 - 4602
SMITH ET AL., NATURE, vol. 321, 1986, pages 674
TET. LET., vol. 46, 2000, pages 8867 - 8871
J. AM. CHEM. SOC., vol. 123, 2001, pages 8101 - 8108
MPODOCLES ET AL., NATURE, vol. 399, 1999, pages 126 - 130
REICHERT ET AL., ANAL. CHEM., vol. 72, 2000, pages 6025 - 6029
LACOSTE ET AL., PROC. NATL. ACAD. SCI USA, vol. 97, no. 17, 2000, pages 9461 - 9466
GUILLIER ET AL., CHEM. REV., vol. 100, 2000, pages 2092 - 2157
J. SAMBROOK ET AL.: "Molecular Cloning: A Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
F.M. AUSUBEL ET AL.: "Short Protocols in Molecular Biology", 1995, JOHN WILEY&SONS, INC.
WELCH ET AL., CHEM. EUR. J., vol. 5, no. 3, 1999, pages 951 - 960
ZHU ET AL., CYTOMETRY, vol. 28, 1997, pages 206 - 211
PROBER ET AL., SCIENCE, vol. 238, 1987, pages 336 - 341
CONNELL ET AL., BIOTECHNIQUES, vol. 5, no. 4, 1987, pages 342 - 384
ANSORGE ET AL., NUCL. ACIDS RES., vol. 15, no. 11, 1987, pages 4593 - 4602
SMITH ET AL., NATURE, vol. 321, 1986, pages 674
TET. LET., vol. 46, 2000, pages 8867 - 8871
J. AM. CHEM. SOC., vol. 123, 2001, pages 8101 - 8108
MPODOCLES ET AL., NATURE, vol. 399, 1999, pages 126 - 130
REICHERT ET AL., ANAL. CHEM., vol. 72, 2000, pages 6025 - 6029
LACOSTE ET AL., PROC. NATL. ACAD. SCI USA, vol. 97, no. 17, 2000, pages 9461 - 9466
GUILLIER ET AL., CHEM. REV., vol. 100, 2000, pages 2092 - 2157
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
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