Title:
OXINDOLE INHIBITORS OF FACTOR Xa
Document Type and Number:
WIPO Patent Application WO2001072708
Kind Code:
A3
Abstract:
Novel compounds of formula (I), including its pharmaceutically acceptable isomers, salts, hydrates, solvates and prodrug derivatives having activity against mammalian factor Xa is described. Compositions containing such compounds are also described. The compounds and compositions are useful in vitro or in vivo for preventing or treating conditions in mammals characterized by undesired thrombosis.
Inventors:
MARLOWE CHARLES K (US)
KANE-MAGUIRE KIM A (US)
ZHU BING-YAN (US)
SCARBOROUGH ROBERT M (US)
KANE-MAGUIRE KIM A (US)
ZHU BING-YAN (US)
SCARBOROUGH ROBERT M (US)
Application Number:
PCT/US2001/009374
Publication Date:
May 23, 2002
Filing Date:
March 26, 2001
Export Citation:
Assignee:
COR THERAPEUTICS INC (US)
MARLOWE CHARLES K (US)
KANE MAGUIRE KIM A (US)
ZHU BING YAN (US)
SCARBOROUGH ROBERT M (US)
MARLOWE CHARLES K (US)
KANE MAGUIRE KIM A (US)
ZHU BING YAN (US)
SCARBOROUGH ROBERT M (US)
International Classes:
A61P7/02; C07D401/12; (IPC1-7): C07D401/12; A61K31/454; A61P7/02
Domestic Patent References:
| WO1999037643A1 | 1999-07-29 | |||
| WO1999000128A1 | 1999-01-07 | |||
| WO1999033800A1 | 1999-07-08 |
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