Title:
OLFACTORY RECEPTOR GENES AND PSEUDOGENES IN PRIMATES AND MOUSE
Document Type and Number:
WIPO Patent Application WO2001046262
Kind Code:
A3
Abstract:
The present invention relates to olfactory receptor genes and pseudogenes of 10 primate species, in addition to mouse. The invention also concerns olfactory receptors encoded by these genes and their utilization.
Inventors:
ROUQUIER SYLVIE (FR)
GIORGI DOMINIQUE (FR)
GIORGI DOMINIQUE (FR)
Application Number:
PCT/IB2000/002017
Publication Date:
April 18, 2002
Filing Date:
December 22, 2000
Export Citation:
Assignee:
CENTRE NAT RECH SCIENT (FR)
ROUQUIER SYLVIE (FR)
GIORGI DOMINIQUE (FR)
ROUQUIER SYLVIE (FR)
GIORGI DOMINIQUE (FR)
International Classes:
C07K14/705; A61K38/00; (IPC1-7): C07K14/705
Foreign References:
| EP0867508A2 | 1998-09-30 |
Other References:
ROUQUIER SYLVIE ET AL: "The olfactory receptor gene repertoire in primates and mouse: Evidence for reduction of the functional fraction in primates.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 97, no. 6, 14 March 2000 (2000-03-14), March 14, 2000, pages 2870 - 2874, XP002180153, ISSN: 0027-8424
SHARON DROR ET AL: "Primate evolution of an olfactory receptor cluster: Diversification by gene conversion and recent emergence of pseudogenes.", GENOMICS, vol. 61, no. 1, 1 October 1999 (1999-10-01), NEW YORK US, pages 24 - 36, XP002180154, ISSN: 0888-7543
ROUQUIER SYLVIE ET AL: "Sequence and chromosomal localization of the mouse ortholog of the human olfactory receptor gene 912-93.", MAMMALIAN GENOME, vol. 10, no. 12, December 1999 (1999-12-01), pages 1172 - 1174, XP000926681, ISSN: 0938-8990
STROTMANN J ET AL: "Small subfamily of olfactory receptor genes: structural features, expression pattern and genomic organization", GENE, ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, NL, vol. 236, no. 2, 20 August 1999 (1999-08-20), pages 281 - 291, XP004178064, ISSN: 0378-1119
MOMBAERTS P: "MOLECULAR BIOLOGY OF ODORANT RECEPTORS IN VERTEBRATES", ANNUAL REVIEW OF NEUROSCIENCE, ANNUAL REVIEWS INC., PALO ALTO, CA, US, vol. 22, 1999, pages 487 - 509, XP000891908, ISSN: 0147-006X
RAMING K ET AL: "CLONING AND EXPRESSION OF ODORANT RECEPTORS", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 361, 28 January 1993 (1993-01-28), pages 353 - 356, XP002029937, ISSN: 0028-0836
ROUQUIER S ET AL: "Distribution of olfactory receptor genes in the human genome", NATURE GENETICS, NEW YORK, NY, US, vol. 18, no. 3, March 1998 (1998-03-01), pages 243 - 250, XP002111208, ISSN: 1061-4036
BEN-ARIE NISSIM ET AL: "Olfactory receptor gene cluster on human chromosome 17: Possible duplication of an ancestral receptor repertoire.", HUMAN MOLECULAR GENETICS, vol. 3, no. 2, 1994, pages 229 - 235, XP001030588, ISSN: 0964-6906
FREITAG J ET AL: "On the origin of the olfactory receptor family: receptor genes of the jawless fish (Lampetra fluviatilis)", GENE, ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, NL, vol. 226, no. 2, 21 January 1999 (1999-01-21), pages 165 - 174, XP004155131, ISSN: 0378-1119
SHARON DROR ET AL: "Primate evolution of an olfactory receptor cluster: Diversification by gene conversion and recent emergence of pseudogenes.", GENOMICS, vol. 61, no. 1, 1 October 1999 (1999-10-01), NEW YORK US, pages 24 - 36, XP002180154, ISSN: 0888-7543
ROUQUIER SYLVIE ET AL: "Sequence and chromosomal localization of the mouse ortholog of the human olfactory receptor gene 912-93.", MAMMALIAN GENOME, vol. 10, no. 12, December 1999 (1999-12-01), pages 1172 - 1174, XP000926681, ISSN: 0938-8990
STROTMANN J ET AL: "Small subfamily of olfactory receptor genes: structural features, expression pattern and genomic organization", GENE, ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, NL, vol. 236, no. 2, 20 August 1999 (1999-08-20), pages 281 - 291, XP004178064, ISSN: 0378-1119
MOMBAERTS P: "MOLECULAR BIOLOGY OF ODORANT RECEPTORS IN VERTEBRATES", ANNUAL REVIEW OF NEUROSCIENCE, ANNUAL REVIEWS INC., PALO ALTO, CA, US, vol. 22, 1999, pages 487 - 509, XP000891908, ISSN: 0147-006X
RAMING K ET AL: "CLONING AND EXPRESSION OF ODORANT RECEPTORS", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 361, 28 January 1993 (1993-01-28), pages 353 - 356, XP002029937, ISSN: 0028-0836
ROUQUIER S ET AL: "Distribution of olfactory receptor genes in the human genome", NATURE GENETICS, NEW YORK, NY, US, vol. 18, no. 3, March 1998 (1998-03-01), pages 243 - 250, XP002111208, ISSN: 1061-4036
BEN-ARIE NISSIM ET AL: "Olfactory receptor gene cluster on human chromosome 17: Possible duplication of an ancestral receptor repertoire.", HUMAN MOLECULAR GENETICS, vol. 3, no. 2, 1994, pages 229 - 235, XP001030588, ISSN: 0964-6906
FREITAG J ET AL: "On the origin of the olfactory receptor family: receptor genes of the jawless fish (Lampetra fluviatilis)", GENE, ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, NL, vol. 226, no. 2, 21 January 1999 (1999-01-21), pages 165 - 174, XP004155131, ISSN: 0378-1119
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