Title:
OLIGOMER ARRAY WITH PNA AND/OR DNA OLIGOMERS ON A SURFACE
Document Type and Number:
WIPO Patent Application WO2001038565
Kind Code:
A3
Abstract:
The invention relates to an oligomer array with PNA (Peptide Nucleic Acid) and/or DNA oligomers on a surface, said oligomers comprising oligomers of 6 to 20 monomers or nucleobases each. Said monomers or nucleobases comprise at least one sequence of the general formula DDCGDD or of the general formula DDTGDD or of the general formula HHCGHH or of the general formula HHCAHH, wherein H represents any of the bases adenine (A), cytosine (C) or thymine (T) and D represents any of the bases adenine (A), guanine (G) or thymine (T). The location of the oligomers on the surface is correlated with the sequence of the oligomers. The inventive oligomer arrays are used to detect cytosine methylations in genomic DNA.
Inventors:
BERLIN KURT (DE)
Application Number:
PCT/DE2000/004301
Publication Date:
November 15, 2001
Filing Date:
November 24, 2000
Export Citation:
Assignee:
EPIGENOMICS AG (DE)
BERLIN KURT (DE)
BERLIN KURT (DE)
International Classes:
C12N15/09; C12Q1/68; C12Q1/6827; C12Q1/6837; (IPC1-7): C12Q1/68
Domestic Patent References:
| WO1999028498A2 | 1999-06-10 | |||
| WO1993025563A1 | 1993-12-23 | |||
| WO1997046705A1 | 1997-12-11 | |||
| WO2001027317A2 | 2001-04-19 |
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