Title:
ONCOLYTIC VIRUS VECTOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/252185
Kind Code:
A1
Abstract:
An oncolytic virus vector and the use thereof in the preparation of a drug for treating a cancer. The oncolytic virus vector contains a recombinant nucleic acid comprising: (i) a first nucleic acid fragment encoding a soluble PD-1 molecule; (ii) a second nucleic acid fragment encoding CD86; and (iii) a third nucleic acid fragment encoding an antibody of a CD3 molecule.
Inventors:
GONG ZIYING (CN)
ZHANG DAOYUN (CN)
SUN YONGHUA (CN)
WANG YI (CN)
SHI NAN (CN)
ZHU JUN (CN)
DING MIAO (CN)
ZHANG DAOYUN (CN)
SUN YONGHUA (CN)
WANG YI (CN)
SHI NAN (CN)
ZHU JUN (CN)
DING MIAO (CN)
Application Number:
PCT/CN2021/098139
Publication Date:
December 08, 2022
Filing Date:
June 03, 2021
Export Citation:
Assignee:
SHANGHAI YUNYING BIOPHARMACEUTICAL TECH CO LTD (CN)
International Classes:
C12N7/01; A61K35/76; A61K35/763; A61K39/00; A61K39/395; A61P35/00; A61P35/02; C12N15/12; C12N15/13; C12R1/93
Domestic Patent References:
| WO2020052551A1 | 2020-03-19 |
Foreign References:
| CN112840020A | 2021-05-25 | |||
| CN108064305A | 2018-05-22 |
Attorney, Agent or Firm:
METIS IP (CHENGDU) LLC (CN)
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