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Title:
OPHTHALMIC COMPOSITION
Document Type and Number:
WIPO Patent Application WO/2024/010043
Kind Code:
A1
Abstract:
The present invention relates to an ophthalmic composition which contains tramadol or a salt thereof and does not substantially contain a preservative agent.

Inventors:
OGAWA YOKO (JP)
Application Number:
PCT/JP2023/024976
Publication Date:
January 11, 2024
Filing Date:
July 05, 2023
Export Citation:
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Assignee:
ROHTO PHARMA (JP)
International Classes:
A61K31/135; A61K9/08; A61K47/18; A61P27/02
Foreign References:
US20190224114A12019-07-25
Other References:
AL-MASHHADANE F.A., MUSTAFA E.A., TAQA G.A.: "Histological and antimicrobial effects of tramadol infiltration on incisional oral mucosal wound healing in rabbits", IRAQI JOURNAL OF VETERINARY SCIENCES, vol. 33, no. 2, 1 September 2019 (2019-09-01), pages 335 - 340, XP093126647, ISSN: 2071-1255, DOI: 10.33899/ijvs.2019.162996
TAMANAI-SHACOORI ZOHREH, SHACOORI VALLIOLLAH, JOLIVET-GOUGEON ANNE, VO VAN JEAN-MARIE, REPÈRE MARTINE, DONNIO PIERRE-YVES, BONNAUR: "The Antibacterial Activity of Tramadol Against Bacteria Associated with Infectious Complications After Local or Regional Anesthesia", ANESTHESIA AND ANALGESIA, WILLIAM AND WILKENS , BALTIMORE , MD, US, vol. 105, no. 2, 1 August 2007 (2007-08-01), US , pages 524 - 527, XP093126659, ISSN: 0003-2999, DOI: 10.1213/01.ane.0000267525.51017.b8
UNLU OZGE, BINGUL EMRE, KESİCİ SEVGI, DEMIRCI MEHMET: "Investigating antimicrobial features and drug interactions of sedoanalgesics in intensive care unit: an experimental study", ADMET AND DMPK, vol. 9, no. 3, pages 219 - 226, XP093126665, ISSN: 1848-7718, DOI: 10.5599/admet.1042
CUVAS APAN OZGUN; OZER MURAT ATABEY; TAKIR SELCUK; APAN ALPARSLAN; SENGUL DEMET: "Effect of topical administration of tramadol on corneal wound healing in rats", INTERNATIONAL OPHTHALMOLOGY., NIJHOFF/JUNK, DORDRECHT., NL, vol. 36, no. 5, 28 January 2016 (2016-01-28), NL , pages 675 - 680, XP036055491, ISSN: 0165-5701, DOI: 10.1007/s10792-016-0184-9
ANONYMOUS: "TRAMOSEL 100 mg / 2 mL I.V./I.M./S.C. ampoule containing solution for injection", PATIENT INFORMATION LEAFLET, 20 September 2013 (2013-09-20), pages 1 - 13, XP093126670
Attorney, Agent or Firm:
HASEGAWA Yoshiki et al. (JP)
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