Title:
OPHTHALMIC EMULSIONS CONTAINING AN IMMUNOSUPPRESSIVE AGENT
Document Type and Number:
WIPO Patent Application WO2006050837
Kind Code:
A3
Abstract:
Ophthalmic oil-in-water emulsions, which comprises colloid particles having an oily core surrounded by an interfacial film, said emulsion comprising an 10 immunosuppressive agent, an oil, preferably at least 50 % of which being MCT, and tyloxapol. Use of such an emulsion for the manufacture of medicament for treatment of eye conditions, particularly of dry eye diseases.
Inventors:
PHILIPS BETTY (FR)
BAGUE SEVERINE (FR)
RABINOVICH-GUILATT LAURA (FR)
LAMBERT GREGORY (FR)
BAGUE SEVERINE (FR)
RABINOVICH-GUILATT LAURA (FR)
LAMBERT GREGORY (FR)
Application Number:
PCT/EP2005/011649
Publication Date:
November 16, 2006
Filing Date:
October 10, 2005
Export Citation:
Assignee:
NOVAGALI PHARMA SA (FR)
PHILIPS BETTY (FR)
BAGUE SEVERINE (FR)
RABINOVICH-GUILATT LAURA (FR)
LAMBERT GREGORY (FR)
PHILIPS BETTY (FR)
BAGUE SEVERINE (FR)
RABINOVICH-GUILATT LAURA (FR)
LAMBERT GREGORY (FR)
International Classes:
A61K9/00; A61K9/107; A61K38/13; A61P27/02
Domestic Patent References:
| WO2003053405A1 | 2003-07-03 |
Other References:
TAMILVANAN S ET AL: "The potential of lipid emulsion for ocular delivery of lipophilic drugs", EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, ELSEVIER SCIENCE PUBLISHERS B.V., AMSTERDAM, NL, vol. 58, no. 2, 1 June 2004 (2004-06-01), pages 357 - 368, XP004526318, ISSN: 0939-6411
DING S ET AL: "CYCLOSPORINE OPHTHALMIC O/W EMULSION: FORMULATION AND EMULSION CHARACTERIZATION", PHARMACEUTICAL RESEARCH, NEW YORK, NY, US, vol. 14, no. 11, SUPPL, November 1997 (1997-11-01), pages S41, XP008005736, ISSN: 0724-8741
DING S ET AL: "CYCLOSPORINE OPHTHALMIC O/W EMULSION: FORMULATION AND EMULSION CHARACTERIZATION", PHARMACEUTICAL RESEARCH, NEW YORK, NY, US, vol. 14, no. 11, SUPPL, November 1997 (1997-11-01), pages S41, XP008005736, ISSN: 0724-8741
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