Title:
ORGANIC SALTS OF N, N'-DIACETYL CYSTINE
Document Type and Number:
WIPO Patent Application WO/1993/011104
Kind Code:
A1
Abstract:
New crystalline organic salts of N, N'-diacetyl cystine with immunomodulating effect, processes for their preparation, pharmaceutical compositons containing them and methods of their pharmacological use.
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Inventors:
ANDERSSON CARL-MAGNUS (SE)
BERGSTRAND HAKAN (SE)
JAKUPOVIC EDIB (SE)
JOSEFSSON BO-GOERAN (SE)
LINDVALL MAGNUS (SE)
SAERNSTRAND BENGT (SE)
TENEBERG ERIC (SE)
BERGSTRAND HAKAN (SE)
JAKUPOVIC EDIB (SE)
JOSEFSSON BO-GOERAN (SE)
LINDVALL MAGNUS (SE)
SAERNSTRAND BENGT (SE)
TENEBERG ERIC (SE)
Application Number:
PCT/SE1992/000807
Publication Date:
June 10, 1993
Filing Date:
November 25, 1992
Export Citation:
Assignee:
ASTRA AB (SE)
International Classes:
A61K31/198; A61K31/205; A61K31/215; A61K31/22; A61K31/195; A61K31/225; A61K31/495; A61P35/00; A61P37/00; A61P37/02; C07C319/24; C07C323/59; C07K5/00; A61K38/00; C07C229/00; (IPC1-7): A61K31/195; A61K31/22; A61K31/225; C07C323/59
Domestic Patent References:
| WO1991018594A1 | 1991-12-12 |
Foreign References:
| EP0300100A1 | 1989-01-25 | |||
| US4827016A | 1989-05-02 | |||
| US4724239A | 1988-02-09 | |||
| US4708965A | 1987-11-24 | |||
| FR2503151A1 | 1982-10-08 | |||
| GB954268A | 1964-04-02 | |||
| SE9002067A | 1990-06-08 | |||
| US4827016A | 1989-05-02 | |||
| US4724239A | 1988-02-09 | |||
| US4708965A | 1987-11-24 | |||
| EP0300100A1 | 1989-01-25 | |||
| DE2326444A1 | 1973-12-06 | |||
| US3647834A | 1972-03-07 | |||
| JPS56155298A | 1981-12-01 | |||
| FR8106592A | 1981-04-02 |
Other References:
Dialog Information Services, File 351, World Patent Index 81-92, Dialog Accession No. 2936022, WPI Accession No. 82-00887E/01, TANABE SEIYAKU KK et al.: "Shampoo comspn. contg. salt of acidic aminoacid or sulphur-contg. N-lower fatty acid acyl-aminoacid with basic aminoacid or their mixt"; & JP,A,56 155 298, 811201,
RADERMECKER, M. ET AL., INT. J. IMMUNOPHARMAC., vol. 10, 1988, pages 913 - 917
SCHEFFER, J.; ARZNEIM ET AL., FORSCH/DRUG RES., vol. 41, 1991, pages 815820
PAUPE, J., RESPIRATION, vol. 58, 1991, pages 150 - 154
BERGSTRAND, H. ET AL., J. FREE RADIC. BIOL. MED., vol. 2, 1986, pages 119 - 127
STEVENSON, F.K., FASEB J, vol. 5, 1991, pages 2250 - 2257
ROSZMAN, T. ET AL., IMMUNOLOGY TODAY, vol. 12, 1991, pages 370 - 374
VAN WAUWE, J.; JANSSEN, P.A.J., INT J. IMMUNOPHARMAC., vol. 13, 1991, pages 3 - 9
ROSENBERG, S.A., IMMUNOLOGY TODAY, vol. 9, 1988, pages 58
KATZ, D.H., TRANSPLANTATION REWIEWS, vol. 41, 1977, pages 77 - 108
VARELA, F.J.; COUTINHO, A., IMMUNOLOGY TODAY, vol. 12, 1991, pages 159 - 166
HANSSON. G.K. ET AL., PROC. NAT. ACAD. SCI. USA, vol. 88, 1991, pages 10530
RADERMECKER, M. ET AL., INT. J. IMMUNOPHARMAC., vol. 10, 1988, pages 913 - 917
SCHEFFER, J.; ARZNEIM ET AL., FORSCH/DRUG RES., vol. 41, 1991, pages 815820
PAUPE, J., RESPIRATION, vol. 58, 1991, pages 150 - 154
BERGSTRAND, H. ET AL., J. FREE RADIC. BIOL. MED., vol. 2, 1986, pages 119 - 127
STEVENSON, F.K., FASEB J, vol. 5, 1991, pages 2250 - 2257
ROSZMAN, T. ET AL., IMMUNOLOGY TODAY, vol. 12, 1991, pages 370 - 374
VAN WAUWE, J.; JANSSEN, P.A.J., INT J. IMMUNOPHARMAC., vol. 13, 1991, pages 3 - 9
ROSENBERG, S.A., IMMUNOLOGY TODAY, vol. 9, 1988, pages 58
KATZ, D.H., TRANSPLANTATION REWIEWS, vol. 41, 1977, pages 77 - 108
VARELA, F.J.; COUTINHO, A., IMMUNOLOGY TODAY, vol. 12, 1991, pages 159 - 166
HANSSON. G.K. ET AL., PROC. NAT. ACAD. SCI. USA, vol. 88, 1991, pages 10530
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