ORNITHINE DECARBOXYLASE VARIANT AND METHOD FOR PRODUCING PUTRESCINE BY USING SAME

WIPO Patent Application WO/2020/138919

A1

The present application relates to: an ornithine decarboxylase or a protein variant thereof; a polynucleotide encoding same; a microorganism containing same; and a method for producing putrescine by using same. The present invention achieves effects of increasing the productivity, production efficiency or production selectivity of putrescine, and reducing costs during putrescine purification by suppressing side reactions.

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LEE JAEHUN (KR)
MOON HEE-SOO (KR)
JEON AE JI (KR)
YANG YOUNG LYEOL (KR)
KIM BYUNG-GEE (KR)
HONG EUN YOUNG (KR)

PCT/KR2019/018404

July 02, 2020

December 24, 2019

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CJ CHEILJEDANG CORP (KR)

C12N9/88; C12P13/00

KR20150009890A	2015-01-27
KR20180136612A	2018-12-26
US20170314007A1	2017-11-02
KR20090107920A	2009-10-14

HACKERT, M. L. ET AL.: "Sequence of ornithine decarboxylase from Lactobacillus sp. strain 30a", JOURNAL OF BACTERIOLOGY, vol. 176, no. 23, December 1994 (1994-12-01), pages 7391 - 7394, XP055721254
HONG, E. Y. ET AL.: "Rational engineering of ornithine decarboxylase with greater selectivity for ornithine over lysine through protein network analysis", JOURNAL OF BIOTECHNOLOGY, vol. 281, 17 July 2018 (2018-07-17), pages 175 - 182, XP055721257

KIM, Aera (KR)

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