Title:
OSMIUM COMPLEXES USABLE AS CATALYSTS FOR THE REDUCTION OF CARBONYL COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2011/033022
Kind Code:
A3
Abstract:
The invention relates to new osmium complexes of the type [OsX2(P2)(diamine)] (P = phosphorus atom of a diphosphine; X = anionic ligand), and to preparation thereof. Said systems, in the presence of bases, have proved to be highly efficient catalysts for the hydrogenation of aldehydes and the enantioselective hydrogenation of various types of ketones.
Inventors:
BARATTA WALTER (IT)
RIGO PIERLUIGI (IT)
MAGNOLIA SANTO (IT)
BARBATO CINZIA (IT)
SIEGA KATIA (IT)
RIGO PIERLUIGI (IT)
MAGNOLIA SANTO (IT)
BARBATO CINZIA (IT)
SIEGA KATIA (IT)
Application Number:
PCT/EP2010/063616
Publication Date:
May 26, 2011
Filing Date:
September 16, 2010
Export Citation:
Assignee:
UNIV DEGLI STUDI UDINE (IT)
BARATTA WALTER (IT)
RIGO PIERLUIGI (IT)
MAGNOLIA SANTO (IT)
BARBATO CINZIA (IT)
SIEGA KATIA (IT)
BARATTA WALTER (IT)
RIGO PIERLUIGI (IT)
MAGNOLIA SANTO (IT)
BARBATO CINZIA (IT)
SIEGA KATIA (IT)
International Classes:
B01J23/46; C07F15/00
Other References:
DOUCET ET AL: "Trans-[RuCl2(phosphine)2(1,2-diamine)] and chiral trans- [RuCl2(diphosphine)(1,2-diamine)]: shelf-stable precatalysts for the rapid, productive, and stereoselective hydrogenation of ketones", ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, WILEY VCH VERLAG, WEINHEIM, vol. 37, no. 12, 1 January 1998 (1998-01-01), pages 1703 - 1707, XP002222044, ISSN: 1433-7851, DOI: DOI:10.1002/(SICI)1521-3773(19980703)37:12<1703::AID-ANIE1703>3.0.CO; 2-I
CLAPHAM S E ET AL: "Reactions of an amido hydrido complex of osmium, OsH(NHCMe 2CMe2NH2)(PPh3)2: HX addition, HX transfer, and ketone H2 Hydrogenation", ORGANOMETALLICS 20050214 AMERICAN CHEMICAL SOCIETY US, vol. 24, no. 4, 14 February 2005 (2005-02-14), pages 479 - 481, XP002571493
BARATTA W ET AL: "Osmium pyme complexes for fast hydrogenation and asymmetric transfer hydrogenation of ketones", CHEMISTRY - A EUROPEAN JOURNAL 20080307 WILEY-VCH VERLAG DE, vol. 14, no. 8, 7 March 2008 (2008-03-07), pages 2557 - 2563, XP002571494
BARATTA W ET AL: "Chiral and nonchiral [OsX2(diphosphane)(diamine)] (X: Cl, OCH2CF3) complexes for fast hydrogenation of carbonyl compounds", CHEMISTRY - A EUROPEAN JOURNAL 20100308 WILEY-VCH VERLAG DEU, vol. 16, no. 10, 8 March 2010 (2010-03-08), pages 3201 - 3206, XP002628732, DOI: DOI:10.1002/CHEM.200902809
CLAPHAM S E ET AL: "Reactions of an amido hydrido complex of osmium, OsH(NHCMe 2CMe2NH2)(PPh3)2: HX addition, HX transfer, and ketone H2 Hydrogenation", ORGANOMETALLICS 20050214 AMERICAN CHEMICAL SOCIETY US, vol. 24, no. 4, 14 February 2005 (2005-02-14), pages 479 - 481, XP002571493
BARATTA W ET AL: "Osmium pyme complexes for fast hydrogenation and asymmetric transfer hydrogenation of ketones", CHEMISTRY - A EUROPEAN JOURNAL 20080307 WILEY-VCH VERLAG DE, vol. 14, no. 8, 7 March 2008 (2008-03-07), pages 2557 - 2563, XP002571494
BARATTA W ET AL: "Chiral and nonchiral [OsX2(diphosphane)(diamine)] (X: Cl, OCH2CF3) complexes for fast hydrogenation of carbonyl compounds", CHEMISTRY - A EUROPEAN JOURNAL 20100308 WILEY-VCH VERLAG DEU, vol. 16, no. 10, 8 March 2010 (2010-03-08), pages 3201 - 3206, XP002628732, DOI: DOI:10.1002/CHEM.200902809
Attorney, Agent or Firm:
GERVASI, Gemma et al. (Corso di Porta Vittoria 9, Milan, IT)
Download PDF: