Title:
OSMOTIC DELIVERY SYSTEM
Document Type and Number:
WIPO Patent Application WO2003063823
Kind Code:
A3
Abstract:
An osmotic pharmaceutical tablet is described which comprises a single-layer compressed core surrounded by a water permeable layer having a passageway. The single-layer core contains (i) a non-ripening drug having a solubility per dose less than about 1 mL<-1>, (ii) about 2.0% to about 20% by weight of a hydroxyethylcellulose having a weight-average, molecular weight from about 300,000 to about 2,000,000, and (iii) an osmagent.
Inventors:
BILLOTE ANNE MARTINE (US)
CARRIER REBECCA LYN (US)
FERGIONE MICHAEL BRUCE (US)
MILLER LEE ANTHONY (US)
ROY MICHAEL CHRISTOPHER (US)
SHAMBLIN SHERI LYNN (US)
WATERMAN KENNETH CRAIG (US)
MACDONALD BRUCE CLINTON (US)
FRIESEN DWAYNE THOMAS (US)
CARRIER REBECCA LYN (US)
FERGIONE MICHAEL BRUCE (US)
MILLER LEE ANTHONY (US)
ROY MICHAEL CHRISTOPHER (US)
SHAMBLIN SHERI LYNN (US)
WATERMAN KENNETH CRAIG (US)
MACDONALD BRUCE CLINTON (US)
FRIESEN DWAYNE THOMAS (US)
Application Number:
PCT/IB2003/000265
Publication Date:
December 04, 2003
Filing Date:
January 28, 2003
Export Citation:
Assignee:
PFIZER PROD INC (US)
BILLOTE ANNE MARTINE (US)
CARRIER REBECCA LYN (US)
FERGIONE MICHAEL BRUCE (US)
MILLER LEE ANTHONY (US)
ROY MICHAEL CHRISTOPHER (US)
SHAMBLIN SHERI LYNN (US)
WATERMAN KENNETH CRAIG (US)
MACDONALD BRUCE CLINTON (US)
FRIESEN DWAYNE THOMAS (US)
BILLOTE ANNE MARTINE (US)
CARRIER REBECCA LYN (US)
FERGIONE MICHAEL BRUCE (US)
MILLER LEE ANTHONY (US)
ROY MICHAEL CHRISTOPHER (US)
SHAMBLIN SHERI LYNN (US)
WATERMAN KENNETH CRAIG (US)
MACDONALD BRUCE CLINTON (US)
FRIESEN DWAYNE THOMAS (US)
International Classes:
A61K47/38; A61K9/00; A61K9/22; A61K9/28; A61K47/10; A61K47/12; A61K47/20; A61K47/26; (IPC1-7): A61K9/00
Domestic Patent References:
| WO2001091716A1 | 2001-12-06 |
Foreign References:
| US5543155A | 1996-08-06 |
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