Title:
OSMOTIC PUMP CONTROLLED RELEASE PREPARATION, OSMOTIC PUMP CONTROLLED RELEASE COMPOSITION, PREPARATION METHOD AND USE
Document Type and Number:
WIPO Patent Application WO/2024/022382
Kind Code:
A1
Abstract:
An osmotic pump controlled release preparation, which comprises the following structures sequentially arranged from inside out: a tablet core containing a drug-containing layer and a push layer, a controlled-release coating layer having a drug release hole, and an optional water-soluble coating film; wherein the drug release hole establishes communication between the drug-containing layer and the outside of the osmotic pump controlled-release preparation; the push layer is located at the side of the drug-containing layer away from the drug release hole; the drug-containing layer comprises an active pharmaceutical ingredient, the push layer comprises an osmopolymer, and the osmopolymer comprises hydroxyethyl cellulose and alginate.
Inventors:
GAN YONG (CN)
ZHU CHUNLIU (CN)
ZHU QUANLEI (CN)
WANG SUYUN (CN)
YOU HENG (CN)
HU JIE (CN)
YAN HU (CN)
ZHU CHUNLIU (CN)
ZHU QUANLEI (CN)
WANG SUYUN (CN)
YOU HENG (CN)
HU JIE (CN)
YAN HU (CN)
Application Number:
PCT/CN2023/109305
Publication Date:
February 01, 2024
Filing Date:
July 26, 2023
Export Citation:
Assignee:
SHANGHAI INST MATERIA MEDICA CAS (CN)
QINGDAO HUANGHAI PHARMACEUTICAL CO LTD (CN)
QINGDAO HUANGHAI PHARMACEUTICAL CO LTD (CN)
International Classes:
A61K9/24; A61K9/36; A61K9/44; A61K31/4422; A61P9/10; A61P9/12
Foreign References:
| CN114053237A | 2022-02-18 | |||
| CN101167700A | 2008-04-30 | |||
| CN101856337A | 2010-10-13 | |||
| CN101732275A | 2010-06-16 | |||
| CN113730370A | 2021-12-03 | |||
| CN105796522A | 2016-07-27 | |||
| CN101496792A | 2009-08-05 |
Attorney, Agent or Firm:
ADVANCE CHINA IP LAW OFFICE (CN)
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