Title:
PROCESS FOR PRODUCING OPTICALLY ACTIVE &agr -METHYLCYSTEINE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2004/063385
Kind Code:
A1
Abstract:
It is intended to provide a process for conveniently and industrially producing an optically active &agr -methylcysteine derivative, which is useful as a drug intermediate and so on, from a less expensive and easily available material. A process for producing a racemic or optically active &agr -methylcysteine derivative which comprises hydrolyzing a racemic or optically active N-carbamyl-&agr -methylcysteine derivative by treating with decarbamylase; and a process for producing an optically active &agr -methylcysteine derivative and an optically active N-carbamyl-&agr -methylcysteine derivative having a configuration opposite to this compound which comprises stereoselectively hydrolyzing a racemic N-carbamyl-&agr -methylcysteine derivative by treating with decarbamylase.
Inventors:
UEDA MAKOTO (JP)
NANBA HIROKAZU (JP)
NANBA HIROKAZU (JP)
Application Number:
PCT/JP2003/015682
Publication Date:
July 29, 2004
Filing Date:
December 08, 2003
Export Citation:
Assignee:
KANEKA CORP (JP)
UEDA MAKOTO (JP)
NANBA HIROKAZU (JP)
UEDA MAKOTO (JP)
NANBA HIROKAZU (JP)
International Classes:
C12N9/80; C12P13/12; C12P41/00; (IPC1-7): C12P41/00; C12N9/80
Domestic Patent References:
| WO2003106689A1 | 2003-12-24 |
Foreign References:
| EP0801131A1 | 1997-10-15 | |||
| EP0725142A1 | 1996-08-07 | |||
| EP0175312A2 | 1986-03-26 |
Attorney, Agent or Firm:
KANEKA CORPORATION (Kita-ku Osaka-shi, Osaka, JP)
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