Title:
PTPase INHIBITORS AND METHODS OF USING THE SAME
Document Type and Number:
WIPO Patent Application WO2003063788
Kind Code:
A3
Abstract:
The present invention relates to protein tyrosine phosphatase ("PTPase") inhibitors, and the use of PTPase inhibitors and PTPase inhibitors in combination with cytokines to treat diseases. Leishmaniasis agents have surprisingly and unexpectedly been found to be potent PTPase inhibitors. Examples of leishmaniasis agents that are also PTPase inhibitors include, but are not limited to, pentavalent antimonial compounds, imidazole compounds, and diamidine compounds. Therapeutic compositions and methods are provided that make use of these compounds to treat diseases.
Inventors:
YI TAOLIN (US)
Application Number:
PCT/US2003/002770
Publication Date:
March 18, 2004
Filing Date:
January 30, 2003
Export Citation:
Assignee:
CLEVELAND CLINIC FOUNDATION (US)
YI TAOLIN (US)
YI TAOLIN (US)
International Classes:
A61K31/29; A61K31/496; A61K31/555; A61K38/19; (IPC1-7): A61K31/44; A01N43/40
Foreign References:
| US6143765A | 2000-11-07 | |||
| US5859065A | 1999-01-12 |
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