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Title:
PACKING MATERIAL FOR SEPARATION OF OPTICAL ISOMER AND METHOD OF SEPARATING OPTICAL ISOMER WITH THE SAME
Document Type and Number:
WIPO Patent Application WO/2002/030853
Kind Code:
A1
Abstract:
A packing for optical-isomer separation with which a mixture of optical isomers can be optically resolved efficiently; and a method of separating optical isomers by simulated moving-bed chromatography in which the packing is used to conduct optical resolution. The packing comprises a support and an optically active polymer deposited thereon in a specific proportion. The method is characterized in that the packing is used to chromatographically isolate the target optical isomer under such conditions as to result in a specific retention volume.

Inventors:
ONISHI ATSUSHI (JP)
MURAZUMI KOICHI (JP)
TACHIBANA KOZO (JP)
Application Number:
PCT/JP2001/009008
Publication Date:
April 18, 2002
Filing Date:
October 12, 2001
Export Citation:
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Assignee:
DAICEL CHEM (JP)
ONISHI ATSUSHI (JP)
MURAZUMI KOICHI (JP)
TACHIBANA KOZO (JP)
International Classes:
B01D15/18; B01D15/38; B01J20/26; B01J20/29; B01J20/32; C07B57/00; (IPC1-7): C07B57/00; B01J20/26; G01N30/48
Foreign References:
JPH0459047A1992-02-25
JPS6238238A1987-02-19
JPS6230549A1987-02-09
EP0154343A21985-09-11
JPH07330802A1995-12-19
JPH06322001A1994-11-22
JPH0658920A1994-03-04
JPH05322866A1993-12-07
EP0471082A11992-02-19
Other References:
NARIO MAKINO: "Iyakuhin seizou ni okeru chiral kagoubutsu no bunri gijutsu", PHARM. TECH. JPN., vol. 12, no. 1, 1996, pages 43 - 52, XP002907902
LUDEMANN-HOMBOURGER O.: "Design of a simulated moving bed: optimal particle size of the stationary phase", SEP. SCI. TECHNOL., vol. 35, no. 9, 2000, pages 1285 - 1305, XP002907903
NARIO MAKINO: "Giji ido shoho ni yoru chiral bunri", KAGAKU KOGAKU, vol. 61, no. 8, 30 April 1997 (1997-04-30), pages 622 - 625, XP002907904
ATSUSHI OHNISHI: "Ekitai chromatography ni yoru kougaku bunkatsu; tatou yuudou taikei koteisou no kaihatsu to bunkatsu tokusei oyobi tairyou bunshu e no ouyou", YUKI GOSEI KAGAKU KYOUKAISHI, vol. 54, no. 5, 1996, pages 344 - 353, XP002907905
TSUNEHIKO KURATA: "Giji ido shoho ni yoru kogaku iseitai no bunri", MITSUBISHI KASEI R&D REVIEW, vol. 6, no. 2, 1992, pages 102 - 105, XP002907906
See also references of EP 1331214A4
Attorney, Agent or Firm:
Fukumura, Naoki (Nishi-Shinjuku 7-chome Shinjuku-ku, Tokyo, JP)
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